We analyze the literature in order to clarify the concept of business model and to identify hotspots business models. Based in those models an in a set of interviews we produced a hotspot business infrastructure model. This model was used to analyze hot spot “industry”, what allowed the identification of several conclusions related to actors’ modus operandi.

LCA is an environmental management tool for assessing the comprehensive environmental impacts of products, processes and activities. Assessment is undertaken along the life cycle from extraction of raw materials, through processing, manufacturing, transportation, use and on to final disposal. This is illustrated by reference to a study of breadmaking wheat production where the relative environm...

One of the major factors that brings complexity to framework development is the identification of its hot spots, i.e., the framework parts that must be kept flexible as they are specific of individual systems. In this paper we show that pattern languages can be important sources for framework hot spots identification and, consequently, can be used for framework construction. We define the types...

Hot spot volcanism may originate from the deep mantle in regions exhibiting the Earth’s most pronounced lateral S-wave velocity gradients. These strong gradient regions display an improved geographic correlation over S-wave velocities to surface hot spot locations. For the lowest velocities or strongest gradients occupying 10% of the surface area of the core–mantle boundary (CMB), hot spots are...

We show that a plasmonic metamaterial can act as a far-field to near-field transformer that focuses a free-space beam of light into a subwavelength energy hot spot at a prescribed location with a spot size only a small fraction of the wavelength. The hot spot position on the metamaterial can be prescribed and moved at will from one metamolecule of the array to another in a "digital" fashion sim...

The aim of this study was to explore the correlations of detectability and the semi-quantification for hot spot imaging with positron emitters in positron emission tomography (PET) and with a positron coincidence detection system (PCD). Phantom study results for the measurement of the lesion-to-background (L/B) ratio ranged from 2.0 to 30.3, and detectability for hot spot lesion of PET and PCD ...

High affinity antibodies are generated in mice and humans by means of somatic hypermutation (SHM) of variable (V) regions of Ig genes. Mutations with rates of 10(-5)--10(-3) per base pair per generation, about 10(6)-fold above normal, are targeted primarily at V-region hot spots by unknown mechanisms. We have measured mRNA expression of DNA polymerases iota, eta, and zeta by using cultured Burk...

We have made deep Chandra observations of three powerful Fanaroff-Riley type II (FR II) radio sources: two quasars (3C 263 and 3C 351) and one radio galaxy (3C 330). X-ray emission from hot spots and lobes, as well as from the active nucleus, is detected in each source. We model the hot spots’ synchrotron spectra using VLA, BIMA, and Hubble Space Telescope data. In 3C 263 and 3C 330, the hot sp...

background: in intracavitary brachytherapy for gynecological cancers, various techniques are used to locate the anterior rectal wall nearest to the sources but there is no consensus on the best method to do so. this study aimed to compare a technique used routinely in some centers that employs a wire marker to locate the position of the maximum rectal dose point, versus the method recommended b...