1. Abstract 2. Introduction 3. Structure and Functions of Choroid Plexus 3.1. Structure of choroid plexus 3.2. Functions of choroid plexus 3.3. Composition of cerebrospinal fluid 4. Ageing of Choroid Plexus 4.1. Anatomical modifications in ageing 4.2. Functional alterations in ageing 4.3. Modification of cerebrospinal fluid in ageing 5. Choroid Plexus and Alzheimer’s Disease 5.1. Anatomical alt...

Room temperature ‘natural’ ageing in Al-Mg-Si alloys was studied by means of six different techniques: electrical resistivity, thermoanalysis, hardness measurement, lifetime of positrons, 3D atom probe and small-angle neutron scattering in order to identify different clustering stages and to study when the negative effect of natural ageing on subsequent ‘artificial’ ageing sets in. The various ...

The age hardening process of a 6082 Al–Mg–Si alloy by isothermal ageing at 100, 125 and 150 °C for 0 to 40 days has been investigated by both conventional and high-resolution transmission electron microscopy. Changes in sizes and densities of the pre-β and β phases during ageing can explain the evolution of hardness, in particular a plateau in the curve of the hardness versus ageing time. Fully...

Brangus steers (n=247) finished on pasture were used to evaluate the effects of post-mortem ageing and polymorphism CAPN1 316 and CAPN1 4751 markers on meat tenderness and objective colour measurements (CIEL*a*b*) of m. Longissimus dorsi. Ageing meat for 7 days decreased shear force (SF) by 13.7% and improved a* (8.4%) and b* (10%) compared to ageing for 1 day. No difference between 7 and 14 da...

Abstract In the mid-1970s the first studies, in the form of inspections of building joints, were conducted in England and Germany into the failure rate of sealants. As a consequence of these studies, the ageing behaviour of sealants was investigated with the aid of artificial accelerated ageing methods and by storing sealants outdoors for several years in moderate or tropical climates. The resu...

DNA damage has been implicated in ageing, but direct evidence for a causal relationship is lacking, owing to the difficulty of inducing defined DNA lesions in cells and tissues without simultaneously damaging other biomolecules and cellular structures. Here we directly test whether highly toxic DNA double-strand breaks (DSBs) alone can drive an ageing phenotype using an adenovirus-based system ...

Increases in human lifespan worldwide have revealed that advancing age is the predominant risk factor for major life-threatening diseases. Recent work has shown that ageing in diverse animals, including humans, is malleable to specific types of genetic mutation, diet, and drugs that can extend lifespan and improve health during ageing. These findings point to the prospect of broad-spectrum prev...

fabrication of ultrafine grained materials by imposing severe plastic deformation for improvement of mechanical and physical properties of metals has been the focus of many researches over the past few years. in this process, a sheet is subjected to repetitive shear deformation conditions by utilizing asymmetrically grooved and flat dies through alternate pressing. in this study, a 2mm thick co...

trajectories generally used to describe the space and time required to perform a desired motion task for a mobile robot or manipulator system. in this paper, we considered a cubic polynomial trajectory for the problem of moving a mobile robot from its initial position to a goal position in over a continuous set of time. along the path, the robot requires to observe a certain acceleration profil...