Entry of the α-coronavirus porcine epidemic diarrhea virus (PEDV) requires specific proteases to activate spike (S) protein for the membrane fusion of the virion to the host cell following receptor binding. Herein, PEDV isolate 85-7 could proliferate and induce cell-cell fusion in a trypsin independent manner on Vero cells, and eight homologous mutation strains were screened by continuous proli...

A frame $L$ is called {it coz-dense} if $Sigma_{coz(alpha)}=emptyset$ implies $alpha=mathbf 0$. Let $mathcal RL$ be the ring of real-valued continuous functions on a coz-dense and completely regular frame $L$. We present a description of the socle of the ring $mathcal RL$ based on minimal ideals of $mathcal RL$ and zero sets in pointfree topology. We show that socle of $mathcal RL$ is an essent...

We present an angiofibroma of soft tissue with the karyotype 46,XY,t(4;5)(q24;q31),t(5;8;17)(p15;q13;q21)[8]/46,XY,t(1;14)(p31;q32)[2]/46,XY[3]. RNA‑sequencing showed that the t(4;5)(q24;q31) resulted in recombination of the genes TBCK on 4q24 and P4HA2 on 5q31.1 with generation of an in‑frame TBCK‑P4HA2 and the reciprocal but out‑of‑frame P4HA2‑TBCK fusion transcripts. The putative TBCK‑P4HA2 ...

Plural unit selection and fusion is a successful method for concatenative synthesis. Yet its unit fusion algorithm is simple and requires improvement. Previous research on unit fusion is mainly involved in boundary smoothing and not quite suitable for the application mentioned above. Therefore, a high-quality unit fusion method is proposed in this paper. More accurate pitch frame alignment and ...

Image fusion is an important process in the medical image diagnostics methods. Fusing images by obtaining information from different source and types of images(modals) called multi-modal fusion. This paper implements effective fast spatial domain based using moving frame decomposition (MFDF)method. Images two modalities are taken decomposed to texture approximation components. Weight mapping st...

In this paper, we propose an efficient continuous-time LiDAR-Inertial-Camera Odometry, utilizing non-uniform B-splines to tightly couple measurements from the LiDAR, IMU, and camera. contrast uniform B-spline-based methods, our B-spline approach offers significant advantages in terms of achieving real-time efficiency high accuracy. This is accomplished by dynamically adaptively placing control ...

As acute nonlymphocytic leukemia (ANLL) with inv(16) (p13q22) or t(16;16)(p13;q22) has been shown to result from the fusion of transcription factor subunit core binding factor (CBFB) to a myosin heavy chain (MYH11), we sought to design methods to detect this rearrangement using reverse transcriptase-polymerase chain reaction (RT-PCR). In all of 27 inv(16)(p13q22) and four t(16;16)(p13;q22) case...

We adapted a fusion polymerase chain reaction (PCR) strategy to synthesize gene disruption alleles of any sequenced yeast gene of interest. The first step of the construction is to amplify sequences flanking the reading frame we want to disrupt and to amplify the selectable marker sequence. Then we fuse the upstream fragment to the marker sequence by fusion PCR, isolate this product and fuse it...