OBJECTIVE To compare the risk of non-fatal venous thromboembolism in women receiving oral contraceptives containing drospirenone with that in women receiving oral contraceptives containing levonorgestrel. DESIGN Nested case-control and cohort study. SETTING The study was based on information from PharMetrics, a United States based company that collects information on claims paid by managed ...

However, the popularity of the method, which was initially very high, has declined precipitously.8 Sales of the device fell from 800 per day in the first quarter of 1994 to about 60 per day in April 1995; the U. S. distributor speculated that “adverse publicity and negative word-of-mouth” drove the decline.9 While both the IUD and oral contraceptives have suffered declines in use attributed to ...

Despite years of family planning effort in Nigeria, the modern contraceptive prevalence (mCPR) has reached only 10%. Yet a few recent seminal, well-executed programs have been outstandingly successful providing long-acting reversible contraceptives (LARCs)—both in the public and private sector, and in the North and South. Remarkably, the LARCs they provided were equivalent to 2% mCPR in 2015 al...

BACKGROUND In India, a large proportion of women with an unmet need for contraception are within their first year after childbirth. Therefore, concentrating efforts to educate postpartum women on the importance of attending contraceptive clinics could have a proportionally bigger impact on increasing postpartum contraception usage. METHODS Hundred and seventy-eight (178) women were followed u...

The emergence or exacerbation of obsessive-compulsive (OC) symptoms during treatment with atypical antipsychotics, mostly clozapine, has been documented by numerous case reports (reviewed by Lykouras et al., 2003). In six recent reports involving nine cases, (Jonkers and de Haan, 2002; Lykouras et al., 2003) olanzapine was found either to cause de novo emergence or to exacerbate OC symptoms. In...

BACKGROUND The birth year-dependent onset of breast cancer (BC) in BRCA1/2 mutation carriers suggests a risk-modifying role for reproductive and life style factors. We therefore examined possible associations between these factors and age at diagnosis. METHODS Cox regression analysis and log-Rank testing were used to estimate the effect of potential life style factors on the onset of BC in 19...

_________________________________________________________________________________ Since the 1960s, oral contraceptives were administered in a traditional 21/7 regimen. In recent years, new regimens (24/4, 84/7, and Lybrel) have reported that shortening the HFI decreases the risk of ovulation and unintended pregnancy. Recent literature also suggests that these regimens are associated with breakt...

The relationship of contraceptive history to diagnostic category of amenorrhoea was analysed in 131 consecutively investigated cases of secondary amenorrhoea. Amenorrhoea occurred in 52 patients immediately after discontinuing the oral contraceptive. Twenty-two had had amenorrhoea before oral contraceptive treatment and 23 patients before the episode of non-contraceptive-related amenorrhoea inv...

In this issue Natural Family Planning ................................................ 2 Menstrual Cycle ........................................................... 13 Contraception .............................................................. 15 Under the Microscope .................................................... 16 Oral Contraceptives, Hormone Replacement Therapy, Breastfeeding and the ...

BACKGROUND It is unclear when in the life course do social inequalities in inflammation emerge. We examined whether the association between socioeconomic position (SEP) and C-reactive protein (CRP) is determined at conception, in childhood, adolescence or adulthood in 1484 participants from the population-based Cardiovascular Risk in Young Finns Study. METHODS Five variants of the CRP gene we...