In this paper, a dynamical multiple criteria model of integrated adaptive planning and scheduling for complex technical – organizational system (CTOS) is presented. Various types of CTOS are used nowadays, for example: virtual enterprises, supply chains, telecommunication systems, etc. Hereafter, we mostly interpret CTOS as the systems of the above-mentioned types. The above-mentioned CTOS pecu...

Background: Integrin recognition of fibronectin is required for normal gastrulation including the mediolateral cell intercalation behaviors that drive convergent extension and the elongation of the frog dorsal axis; however, the cellular and molecular mechanisms involved are unclear. Results: We report that depletion of fibronectin with antisense morpholinos blocks both convergent extension and...

While it is generally assumed that global plate motions are driven by the pattern of convection in the Earth’s mantle, the details of that link remain obscure. Bouyancy forces associated with subduction of cool, dense lithosphere at zones of plate convergence are thought to provide significant driving force, but the relative magnitudes of other driving and resisting forces are less clear, as ar...

Occam's razor, the principle of parsimony, is a tool that finds application in many areas of science. Its validity has never been proven in full generality from first principles. Convergent guessing is the property th at as more examples of an input-output mapp ing are provided , one would expect the modelling of that mapping to become mor e and more accurate. It too is widely used and has not ...

Hyperbolic quadratic matrix polynomials Q(λ) = λ2A + λB + C are an important class of Hermitian matrix polynomials with real eigenvalues, among which the overdamped quadratics are those with nonpositive eigenvalues. Neither the definition of overdamped nor any of the standard characterizations provides an efficient way to test if a given Q has this property. We show that a quadratically converg...

Epithelial remodeling determines the structure of many organs in the body through changes in cell shape, polarity and behavior and is a major area of study in developmental biology. Accurate and high-throughput methods are necessary to systematically analyze epithelial organization and dynamics at single-cell resolution. We developed SEGGA, an easy-to-use software for automated image segmentati...

The formation of the head and trunk-tail organizers in the dorsal marginal zone (DMZ) of an amphibian embryo is thought to require spatial and temporal interactions between the Nieuwkoop center and the DMZ. Recent studies of the Xenopus embryo suggested that intra-DMZ interaction is also needed to establish the regional specificity of the DMZ. However, it is not yet clarified when and how the f...

This paper investigates the effects of heat and mass transfer on unsteady MHD Nanofluid flow (silver-water) through convergent-divergent channel. The governing equations this study are non-linear partial differential these were reduced to ordinary equations. resulting have been a system first order solved using collocation method via bvp4c in MATLAB. It is found that nanoparticle volume fractio...

The Xenopus gene crescent encodes a member of the secreted Frizzled-related protein (sFRP) family and is expressed in the head organizer region. However, the target and function of Crescent in early development are not well understood. Here, we describe a role of Crescent in the regulation of convergent extension movements (CEMs) during gastrulation and neurulation. We show that overexpression ...