Epidemiological and recent prospective analyses of long Febrile Seizures (FS) support the idea that such seizures can provoke Temporal Lobe Epilepsy (TLE) in some children. Because of the high prevalence of these seizures, if epilepsy was to arise as their direct consequence, this would constitute a significant clinical problem. Animal studies have revealed that exposure of hippocampal neurons ...

1.1 First reports on epilepsy The history of epilepsy is intervened with the history of humanity. One of the first descriptions of epileptic seizures can be traced back to 2,000 B.C. in ancient Akkadian texts, a language widely used in the region of Mesopotamia. The author described a patient with symptoms resembling epilepsy: his neck turns left, his hands and feet are tense and his eyes wide ...

OBJECTIVE The aim of this study was to investigate the effect of demographic and clinical characteristics on temporal changes in seizure control and frequency in medically treated epilepsy patients to guide treatment modalities. METHODS We retrospectively analyzed the association between clinical and demographic characteristics and seizure frequency in 1329 epilepsy patients who were followed...

Objective(s): Fasted rodents treated with antimuscarinics develop convulsions after refeeding. Food deprivation for 48 hr produces changes in [3H]glutamate binding suggesting glutamatergic contribution to the underlying mechanism of the seizures that are somewhat unresponsive to antiepileptics. Studies in animals and epileptic patients yielded considerable information regarding the anticonvulsa...

The term 'myoclonic epilepsy' is used in adults to describe a form of epilepsy in which a sudden, involuntary, and momentary contraction occurs in a single muscle or muscle group, often without apparent loss of consciousness. Such attacks may occur in isolation, or as part of the pattern of epilepsy in patients experiencing grand mal or other forms of epilepsy. A recent authoritative review of ...

Objective: Neonatal convulsions may be an early sign of brain injury and the presence in neonatal period has been associated with long-term sequelaes such as mental retardation, postnatal epilepsy death. We aimed to determine associations etiological factors neurodevelopment postneonatal evaluate risk newborns that were not related hypoxic-ischemic encephalopathy. Material Methods: This study i...

Objective: This study aims at identifying the different presentations of infantile epilepsy with their E.E.G. and neuro-radiological patterns. Patient & Methods: Patients included in this study were children suffering from epilepsy starting below 2 years of age. They were attending the outpatient clinic or were from the in-patient departments in Prince Ali – Ben Al Hussein hospital. The study i...

BACKGROUND This study investigated whether long-term treatment with antiepileptic drugs (AEDs) had negative effects on statural growth and serum calcium levels in children with epilepsy in Taiwan. METHODS Children with epilepsy treated with one prescription of AEDs (monotherapy) for at least 1 year were selected. The AEDs included valproic acid (VPA; Deparkin) in 27 children (11 boys and 16 g...