introduction: the fetus needs a considerable amount of cholesterol for the development of tissues and organs.  studies have suggested that genetic and environmental factors influence the composition of cord blood lipoproteins.  in this study, we aim to assess the effect of gestational age, sex and birth weight on the cord blood lipoproteins. methods: we collected umbilical cord blood samples fr...

background: induced pluripotent stem cells (ipscs) can be obtained from autologous cells for therapeutic purposes. so, far, many studies have been done to produce induced pluripotent cells by transferring specific pluripotency genes using different methods. in this study, pluripotency gene expression induced by external stresses was assessed in cord blood mononuclear cells. methods: in this exp...

The good outcome of hematopoietic stem cell (HSC) transplantation is hampered by low doses of CD34+ cell infusion. Transplanted HSCs undergo a replicative stress that causes accelerated senescence due to rapid telomere shortening. The expansion of human cord blood HSCs is instrumental in obtaining a large number of "good quality" cells, in terms of telomere length and telomerase activity compar...