THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS GUIDELINES ON HEMATOPOIETIC STEM CELL

Hematopoietic stem-cell transplantation (HSCT) refers to a procedure in which hematopoietic stem cells are infused to restore bone marrow function in cancer patients who receive bone-marrowtoxic doses of cytotoxic drugs, with or without whole body radiation therapy. Stem cells may be obtained from the transplant recipient (autologous HSCT) or can be harvested from a donor (allogeneic HSCT). Ste...

HSCT was performed.6 John Goldman was widely respected in the fi eld of haematology and he was one of the pioneers who laid the foundation stones for the fi eld of unrelated donor marrow transplantation.7 Together with Professor Jon Van Rood, who made crucial discoveries in the role of HLA and laid the groundwork for the tissue typing that would make blood stem cell transplants possible, Profes...

introductio: hematopoietic stem cell transplants (hsct) are considered as treatment options for patients with solid tumors. transplant numbers have changed significantly over the last decade. we have done autologous and allogeneic hsct for treatment of solid tumor patients in our center. methods: in order to show the transplant effect on solid tumor treatment, we collected data from 71 patients...

tissue and cell transplantation are regarded as a popular procedure in clinical sciences, prospecting a new horizon for several incurable diseases. along with its usefulness, many ethical concerns accompany this development. the ethical issue of organ transplant is unique to the source used which includes: living related, living unrelated, cadaveric, and xenotransplant. obtaining organs has a s...

Background and Objective: Umbilical Cord blood (UCB) hematopoietic stem cell (HSC) transplantation is a therapeutic approach for the treatment of malignant and non-malignant hematologic disorders due to ease of collection, lack of risk for donors and lower levels of infection. Moreover, it is considered a good alternative for bone marrow HSC transplantation. The main limitation of their use is ...

background: in this study, we examined a new two step induction protocol for improving the differentiation of human umbilical cord blood-derived mesenchymal stem cells into neural progenitor cells. materials and methods: human umbilical cord blood-derived mesenchymal stem cells were first cultured in dulbecco’s modified eagle medium supplemented with 10% fetal bovine serum in a humidified incub...

THE BRAZILIAN SOCIETY FOR BLOOD AND MARROW TRANSPLANTATION (SBTMO) PRESENTS GUIDELINES ON HEMATOPOIETIC STEM CELL

background: unrestricted somatic stem cells (ussc) are cord blood stem cells that have been considered as candidates for the regulation of immune responses. therefore, potential exists for their use in the suppression of immune response after transplantation surgery. objective: the aim of this study was evaluation of the effect of ussc on mixed lymphocyte reaction (mlr) as a model for graft rej...