OBJECTIVE Carbon monoxide (CO) is a weak soluble guanylyl cyclase stimulator, leading to transient increases in cGMP and vasodilation. The aim of the present work was to measure the effect of CO-releasing molecules (CORMs) on the cGMP/nitric oxide (NO) pathway and to evaluate how selected CORMs affect NO-induced vasorelaxation. METHODS AND RESULTS Incubation of smooth muscle cells with some b...

Photometric clustering of regenerated plants of gladiolus was described using fuzzy adaptive resonance theory (ART) and the resultant grouping pattern was compared with ART 2, and self-organizing map (SOM) neural network modules. Classical clustering techniques such as hierarchical (HC) and k-means clustering (KM)were also applied to analyze the same data set to evaluate the performance of the ...

We investigated the metabolism of mouse isolated heart under influence tricarbonyldichlorothenium (II)- dimer (CORM-2 and 2,3-4,5-bis-O-isopropylidene-βD-fructopyranose sulfamate (topiramate) as potential blockers aquaporine channel (AQP3) cardiac myocytes. The results were compared with those obtained from group receiving anti-AQP3 monoclonal antibodies. A decrease in coronary flow was found d...

the saffron understanding the factors that increased the quality and quantity of product in order to achieve optimum performance it is important, in this regard, the use of fertilizers and different densities corm are the most important factor. in this regard, an experiment in 1394 to factorial design in a randomized complete block design with three replications in the village davoodabad locate...

Heme oxygenase-1-derived carbon monoxide prevents inflammatory vascular disorders. To date, there is no clear evidence that HO-1/CO prevents endothelial dysfunction associated with the downregulation of endothelial NO synthesis in human endothelial cells stimulated with TNF-α. Here, we found that the CO-releasing compound CORM-2 prevented TNF-α-mediated decreases in eNOS expression and NO/cGMP ...

During radiotherapy procedures, radiation-induced bystander effect (RIBE) can potentially lead to genetic hazards to normal tissues surrounding the targeted regions. Previous studies showed that RIBE intensities in cell cluster models were much higher than those in monolayer cultured cell models. On the other hand, low-concentration carbon monoxide (CO) was previously shown to exert biological ...

Better irrigation management and more efficient management of crop production require modeling of plant growth and crop yield. More applicable models are usually simple and requires less and accessible inputs. The objective of this study was to develop a model for growth and yield prediction of saffron under various irrigation regimes. In this modeling soil water budget and other simple rel...

1. The orchid Tipularia discolor possesses two to five subterranean corms containing a high concentration of total non-structural carbohydrates (TNC). W e investigated the role of corms in the initiation of new growth following seasonal dormancy, in reproduction, and in the response of plants to artificial defoliation. 2. Severance of older corms (representing c. 3O0/0 of total corm biomass) in...