Chloroquine is frequently used to treat systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). With long term treatment, associated toxicity is well known, with retinopathy been the most common complication. Other chronic complications include skin disorders (hyperpigmentation), blood dyscrasias, corneal deposits, encephalopathy, neuropathy, myopathy, and impairment of audito...

Patients have been very satisfied with these lenses (78% wearing at the end of six months), not the least those with reduced function of the macula. The problems of infection have been discussed, and apart from improvement in lens materials patient selection is of paramount importance. The problem of deposits is presented, but theri elimination will depend on more research into their nature and...

Contact lenses are used as a method of correcting refractive errors. However, their use can be associated with periods of discomfort as well as occasional pathophysiological reactions. This inaugural edition of Optometry Rounds presents the latest findings to allow Optometrists to improve the experience of their patients who wear contact lenses, as well as to share knowledge with respect to con...

Chloroquine is frequently used to treat systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). With long term treatment, associated toxicity is well known, with retinopathy been the most common complication. Other chronic complications include skin disorders (hyperpigmentation), blood dyscrasias, corneal deposits, encephalopathy, neuropathy, myopathy, and impairment of audito...

Stromal corneal dystrophies are a group of hereditary disorders caused by mutations in the TGFBI gene. The mutant TGFBIp is prone to protein aggregation and gets deposited cornea, leading severe visual impairment. lead specific suggesting involvement tissue-specific factors. exact molecular mechanism process remains be elucidated. Differential proteolysis critical component disease pathology. d...

Abstract To report novel ocular findings in unique Marinesco-Sjögren syndrome (early-onset cataracts, cerebellar ataxia, and a progressive myopathy), review literature, discuss causes of vision decrease this rare entity. A 3-year-old girl diagnosed with underwent uneventful cataract surgery both eyes within 1 week her 2nd birthday. This was exactly similar to sister other two related family mem...

In the present study, the effects of the acute and chronic oral administrations (po) of curcumin in the absence and presence of morphine and naloxone was investigated on the sensation of acute corneal pain in rats. Acute corneal pain was induced by the local application of hypertonic saline (5 M NaCl) on the corneal surface, and the number of eye wipes was then counted for 30 s. Subcutaneous (s...