reliable, exclusively in appropriately selected situations. In creation of bypass grafts, durable completeness of revascularization and function of the ITA to the LAD bypass should not be compromised. We would suggest that the balanced bypass flow toward the LAD and the RCA is noticeably important to achieve an entire patency of the Y-graft for three-vessel regions. This study is not conclusive...

BACKGROUND Gene therapy is a rational approach to prevention of stenosis in saphenous vein grafts used as conduits for coronary artery bypass grafting. To explore this possibility we developed methods for adenoviral-mediated gene transfer to canine saphenous veins. METHODS During a single procedure, autogenous canine saphenous vein segments were transduced ex vivo and used as coronary artery ...

AIMS To investigate the clinical predictors of coronary atherosclerosis and to assess the utility of maximum-IMT for predicting coronary atherosclerosis in asymptomatic type 2 diabetic patients. METHODS One hundred one Japanese patients with type 2 diabetes underwent computed tomography coronary angiography. Definitions of coronary artery stenosis and vulnerable coronary plaque were luminal n...

Vascular graft stenosis after infrainguinal vein grafting or coronary artery bypass graft surgery is a significant cause of morbidity and suboptimal long-term clinical outcome of patients with vascular disease. Numerous animal and clinical studies have been undertaken to reveal the pathophysiological mechanisms accounting for this detrimental process. Stenotic lesions are dominated by neointima...

BACKGROUND Coronary artery bypass grafting success is limited by vein graft failure (VGF). Understanding the factors associated with VGF may improve patient outcomes. METHODS AND RESULTS We examined 1828 participants in the Project of Ex Vivo Vein Graft Engineering via Transfection IV (PREVENT IV) trial undergoing protocol-mandated follow-up angiography 12 to 18 months post-coronary artery by...

Coronary artery disease is the single leading cause of death in the United States. Every year more than 1 million open coronary revascularization procedures are performed in the United States. Most commonly the greater saphenous veins and internal mammary and/or radial arteries are used as bypass conduits. Long term patency and avoiding repeat revascularization is every surgeon’s goal following...

In recent years, percutaneous endovascular intervention has become the primary treatment for pediatric post-liver transplantation portal vein stenosis. This procedure is usually performed using a transhepatic approach. Herein, we report the transsplenic endovascular management of a 3-year-old girl with post-liver transplantation, late-onset portal vein occlusion, which occurred after repeated p...

PURPOSE To evaluate the diagnostic performance of left coronary bifurcation angles and plaque characteristics for prediction of coronary stenosis by dual-source CT. METHODS 106 patients suspected of coronary artery disease undergoing both coronary computed tomography angiography (CCTA) and invasive coronary angiography (CAG) within three months were included. Left coronary bifurcation angles ...

Case presentation An 81-year-old man was admitted to our institution with symptoms and signs consistent with acute lung oedema. He had a history of hypertension and hypercholesterolaemia and had undergone cardiac surgery in July 2005 due to severe aortic stenosis and three vessels disease. Coronary artery bypass grafting (CABG) with a saphenous vein graft (SVG) to left anterior descending (LAD)...