When I prepared the title and the abstract for this paper in mid-September last year I had no idea that, within days, the three-time elected Thaksin government would be overthrown by a military coup. This coup was very unfortunate for democracy in Thailand but it was rather more fortunate for my paper as the coup, and the reaction to it, underlined many of the points I was planning to make abou...

The CCAAT box is one of the conserved motifs found in globin promoters. It binds the CP1 protein. We noticed that the CCAAT-box region of embryonic/fetal, but not adult, globin promoters also contains one or two direct repeats of a short motif analogous to DR-1 binding sites for non-steroid nuclear hormone receptors. We show that a complex previously named NF-E3 binds to these repeats. In trans...

We previously identified various upstream and downstream regulatory elements and factors important for hepatic expression of the human angiotensinogen (ANG) gene, the precursor of vasoactive octapeptide angiotensin II. In the present study, to further investigate the molecular mechanism of human ANG transcriptional regulation, we generated transgenic mice carrying the fusion gene composed of th...

The surface levels of major histocompatibility complex class I antigens are diminished on tumorigenic adenovirus type 12 (Ad12)-transformed cells, enabling them to escape from immunosurveillant cytotoxic T lymphocytes (CTLs). This is due to the down-regulation of the class I transcriptional enhancer, in which there is strong binding of the repressor COUP-TFII and lack of binding of the activato...

The author explores the different temporalities of developmental time, après-coup and what she calls 'reverberation time'. She considers the paradoxical temporality of the 'here and now', showing that it is not pure present, and describes at the micro-level of sessional material how progressive and retrospective time go inherently together, one being a requisite for the other.

When the head is subject to non-penetrating (blunt) impact, contusion-type injuries are commonly identified beneath the impact site (the coup) and, in some instances, at the opposite pole (the contre-coup). This pattern of injury has long eluded satisfactory explanation and blunt head injury mechanisms in general remain poorly understood. There are only a small number of studies in the open lit...

Abstract This paper offers a novel illustration of the political economy religion by examining impact religious elites on development. We compile unique database holy Muslim shrines across Pakistani Punjab and construct historical panel literacy spanning over century (1901–2011). Using 1977 military takeover as universal shock that gave control public goods to politicians, our difference-in-dif...

Clara cell 10 kD protein (CC10) is expressed specifically in a portion of nonciliated airway epithelial cells. The molecular mechanisms that determine its high specificity are not clear. Transcription factors implicated in the regulation of CC10 in rodents do not show the same level of cell specificity. We report here that a 3.3 kb human CC10 DNA fragment, containing the 5' flanking region and ...