AIM To understand how a cancer precision medicine tumor board (CPM-TB) made choices about return of results. MATERIALS & METHODS Observed CPM-TB deliberations and completed in-depth interviews with committee members. RESULTS Responding to complex evidence of ambiguous significance, deliberations of the CPM-TB were predicated on analytic validity and clinical utility. Members had concerns bo...

Dagger compact closed categories were studied by Abramsky and Coecke (under the name “strongly compact closed categories”) as an abstract presentation of the category of Hilbert spaces and linear maps, and as a framework in which to carry out the interpretation of quantum protocols. I subsequently showed that dagger compact closed categories can also describe mixed quantum computation, where th...

Demyelination is a hallmark of central pontine myelinolysis (CPM). Neuropsychiatric manifestations of this condition include weakness, quadriplegia, pseudobulbar palsy, mood changes, psychosis, and cognitive disturbances. These psychiatric symptoms are also associated with schizophrenia and alcohol withdrawal. Thus, it is clinically relevant to differentiate between CPM, schizophrenia, and alco...

Recently, new technology that supports human will be an emergent issue as population ages and birthrate declines. As human having a lot of joints utilizes many degrees of freedom (d.o.f.) for living and working, reduction or loss of d.o.f. will deteriorate the quality of life. So, it will be important to recover joint functions immediately after injury or operation. Accordingly, many studies ha...

The Closest Point Method (CPM) is a method for numerically solving partial differential equations (PDEs) on arbitrary surfaces, independent of the existence of a surface parametrization. The CPM uses a closest point representation of the surface, to solve the unmodified Cartesian version of a surface PDE in a 3D volume embedding, using simple and well-understood techniques. In this paper we pre...

INTRODUCTION Central pontine myelinolysis (CPM) is an acquired demyelinating lesion of the basis pontis that typically occurs after rapid correction of hyponatremia. There are only a few reported cases of patients without symptoms that have demonstrated CPM on imaging. CASE PRESENTATION We report the case of a 26-year-old Hispanic male with history of alcohol abuse who was transferred to our ...

BACKGROUND Several chronic pain populations have demonstrated decreased conditioned pain modulation (CPM). However there is still a need to investigate the stability of CPM paradigms before the measure can be recommended for implementation. The purpose of the present study was to assess whether shoulder pain intensity and gender influence CPM stability within and between sessions. METHODS Thi...

Various management approaches have been proposed to maintain good organizational performance on a continuous basis, with corporate (CPM) and business process (BPM) being two major groups. While the conceptual connection between CPM BPM might see obvious, their actual empirical remains poorly understood. In this article, we address gap develop theoretical model that explicates causal paths from ...