The endocannabinoids and their main receptor, cannabinoid type-1 (CB1), suppress intracellular cyclic AMP levels and have emerged as key players in the control of energy metabolism. CB1 agonists and blockers have been reported to influence the thermogenic function of white and brown adipose tissue (WAT and BAT), affecting body weight through the inhibition and stimulation of energy expenditure,...

This study analyzed growth patterns, biological compounds, antioxidant properties, ginsenoside contents, metabolites, and the annual net production of ‘Yunpoong’ ‘K-1’ to find optimal harvesting time ginseng sprouts. One-year-old seedlings were cultivated in a container-type vertical farm under temperature 20 °C, humidity 60%, average light intensity 46.4 µmol m−2 s−1 (16 h photoperiod). Growth...

The first purpose of this study was to investigate whether a GLU+FRUC beverage would result in a higher exogenous CHO oxidation rate and a higher fluid availability during exercise in the heat compared with an isoenergetic GLU beverage. A second aim of the study was to examine whether ingestion of GLU at a rate of 1.5 g/min during exercise in the heat would lead to a reduced muscle glycogen oxi...

Age-linked metabolic disturbances, such as liver steatosis and insulin resistance, show greater prevalence in men than in women. Thus, our aim was to analyze these sex-related differences in male and female Wistar rats (aged 26 days and 3, 7, and 14 months), and to assess their potential relationship with alterations in the capacity of adipose tissue expansion and the dysregulation of the main ...

BACKGROUND Incomplete reporting is a frequent waste in research. Our aim was to evaluate the impact of a writing aid tool (WAT) based on the CONSORT statement and its extension for non-pharmacologic treatments on the completeness of reporting of randomized controlled trials (RCTs). METHODS We performed a 'split-manuscript' RCT with blinded outcome assessment. Participants were masters and doc...

Onlangs deed een groep prominenten, waaronder Elon Musk, oproep voor moratorium van zes maanden op de ontwikkeling AI-systemen, zoals ChatGPT. Hoe moeten we deze beoordelen? Wat zouden Marshall McLuhan en Karl Marx hiervan vinden? En wat gaat AI betekenen beleidsonderzoek? Daarover column.

Bofutsushosan (BOF), an oriental herbal medicine, has been used as an anti-obesity drug in overweight patients. In the present study, to evaluate the anti-obesity and anti-diabetic effects of BOF, we investigated the effects of BOF on the white adipose tissue (WAT) weight, the size of adipocytes, adiponectin expression, and oral glucose tolerance test results in high-fat diet-fed male KK/Ta mic...

A baseline study of soil-transmitted helminthiases was carried out in Nakhon Si Thammarat Province, southern Thailand. The study sites were Wat Krou Chou Primary School and nearby villages in Sichon district, and Wat Thang Phoon Primary School and nearby villages in Chalerm Phrakiat District. Surveys of the schoolchildren's stools were conducted by the Kato-Katz technique. The results showed th...