OBJECTIVE The study evaluated associations between outcome measures used in driving research including self-reported crashes, state crash records, and an on-road driving test (ORT). METHOD A total of 750 community dwelling participants aged 69 to 95 were recruited via the electoral roll into a study on injury prevention. Of these, 509 were drivers, and data on self-reported crashes, and eithe...

PURPOSE To determine the role of vision and visual attention factors in automobile crash involvement. METHODS Drivers aged 65 to 84 years were identified during the baseline interview (1993-1995) of the Salisbury Eye Evaluation (SEE) Study. Crash involvement through December 1997 was determined from Maryland State motor vehicle records. Vision tests at baseline included distance acuity at nor...

Graduated driving licensing laws are now in place in all 50 U.S. states and the District of Columbia. However, despite stricter supervised driving requirements, restrictions on the number of passengers, and earlier nighttime driving curfews, teen drivers continue to be at a higher crash risk than the adult driving population. The National Motor Vehicle Crash Causation Survey (NMVCCS) dataset wa...

There has been considerable research conducted over the last 20 years focused on predicting motor vehicle crashes on transportation facilities. The range of statistical models commonly applied includes binomial, Poisson, Poisson-gamma (or Negative Binomial), Zero-Inflated Poisson and Negative Binomial Models (ZIP and ZINB), and Multinomial probability models. Given the range of possible modelin...

Meiotic recombination is required for the orderly segregation of chromosomes during meiosis and for providing genetic diversity among offspring. Among mammals, as well as yeast and higher plants, recombination preferentially occurs at highly delimited chromosomal sites 1-2 kb long known as hotspots. Although considerable progress has been made in understanding the roles various proteins play in...

Quantitative trait loci (QTL) hotspots (genomic locations affecting many traits) are a common feature in genetical genomics studies and are biologically interesting since they may harbor critical regulators. Therefore, statistical procedures to assess the significance of hotspots are of key importance. One approach, randomly allocating observed QTL across the genomic locations separately by tra...

The available data, mainly topography, geoid, and heat flow, describing hotspots worldwide are examined to constrain the mechanisms for swell uplift and to obtain fluxes and excess temperatures of mantle plumes. Swell uplift is caused mainly by excess temperatures that move with the lithosphere plate and to a lesser extent hot asthenosphere near the hotspot. The volume, heat, and buoyancy fluxe...

Driving speed is an important factor in road safety. Speed not only affects the severity of a crash, but is also related to the risk of being involved in a crash. This paper discusses the most important empirical studies into speed and crash rate with an emphasis on the more recent studies. The majority of these studies looked at absolute speed, either at individual vehicle level or at road sec...

The use of endemism and vascular plants only for biodiversity hotspot delineation has long been contested. Few studies have focused on the efficacy of global biodiversity hotspots for the conservation of insects, an important, abundant, and often ignored component of biodiversity. We aimed to test five alternative diversity measures for hotspot delineation and examine the efficacy of biodiversi...

BACKGROUND The spread of infectious diseases in wildlife populations is influenced by patterns of between-host contacts. Habitat "hotspots"--places attracting a large numbers of individuals or social groups--can significantly alter contact patterns and, hence, disease propagation. Research on the importance of habitat hotspots in wildlife epidemiology has primarily focused on how inter-individu...