We assessed 16 patients before and after high tibial osteotomy by electrophysiological recordings, creatine phosphokinase levels, radiographs and intracompartmental pressure monitoring. We found mild electrophysiological abnormalities pre-operatively in 12 of the 16 patients, but postoperatively these had deteriorated in 11 of the 14 patients studied. Creatine phosphokinase levels, compartment ...

The usefulness of measuring creatine kinase MB isoenzyme for diagnosing myocardial infarction when activities of total creatine kinase are very high is unclear. We conducted a retrospective study in an urban hospital that serves a largely indigent population. We concentrated on 146 patients whose creatine kinase activity was greater than 1000 U/L (upper limit of normal: 165 U/L for women and 22...

Three healthy young men participating in phase 1 clinical vaccine trials had unexplained increases in their serum transaminase levels. Retrospective analysis indicated that these volunteers had participated in strenuous physical training 2-5 days prior to the noted elevations. The pattern of serum enzyme elevations, initially thought to be consistent with hepatic injury, were associated with pa...

Extracts of embryonic mouse tissues (skeletal, cardiac and smooth muscle, and brain) were analysed by Cellogel electrophoresis for their isoenzymic distributions of three enzymes, creatine phosphokinase, aldolase and phosphoglycerate mutase. Embryonic tissues from the 12th day to the end of gestation were examined for isoenzyme transitions, and it was found that the adult forms of these enzymes...

C rush injury leading to rhabdomyolysis is one of the dreaded complications of natural catastrophes such as earthquakes. Rhabdomyolysis is a syndrome characterized by muscle necrosis and the release of intracellular muscle constituents, namely creatine phosphokinase, myoglobin, and various electrolytes into the circulation. Precipitation of myoglobin in the renal tubules with secondary obstruct...

Abstract Funding Acknowledgements Type of funding sources: None. Introduction / Purpose The extent myocardial injury is a prognostic factor in patients with infarction presenting without persistent ST elevation (NSTEMI). purpose this study was the assessment possible correlation between novel echocardiographic indices and biomarkers NSTEMI normal left ventricular ejection fraction (LVEF). Metho...