BACKGROUND AND OBJECTIVE The aim of this study was to measure contemporaneously HCV-RNA load, HIV-RNA load and CD4+ lymphocyte count in HCV/HIV coinfected patients with coagulopathy and to examine the relationship between these parameters and the liver failure. DESIGN AND METHODS A cross-sectional study was performed on 54 patients with severe coagulopathy: 39 HCV/HIV coinfected and 15 HCV+/H...

Lightweight steel framing is a method in housing and construction that have been widely used in lightweight steel construction. In this method, the structure is built by cold formed steel elements. They are cost-effective, light, and easy to assemble. However, the performance of lateral load resisting systems in cold-formed steel structures specially the behavior of cold-formed steel shear wall...

This study evaluated the effect of macro steel fiber (SF), micro glass fiber (GF) and micro polypropylene fiber (PF) in lightweight aggregate concrete, (LWAC) beams reinforced with glass fiber reinforced polymer (GFRP) bars. Firstly, concrete mixtures with different volume fractions of GF, PF and SF were tested up to compressive strength, then determine the optimum fiber content GF, PF and SF a...

Abstract The static lateral load–slip behavior of a single-shear plywood-to-plywood single-staple connection (SPSC) was investigated experimentally. A mechanics-based approach used to develop mechanical models for deriving estimation equations critical loads SPSCs based on failure modes staple legs and member materials developed during loading process. Experimental results indicated that the ca...

OBJECTIVE We systematically reviewed the performance of 2010 WHO immunologic and clinical criteria for predicting virologic failure in HIV-infected patients on antiretroviral therapy (ART). DESIGN Systematic review. METHODS We used Cochrane Collaboration methods. We calculated unweighted sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of immuno...

In this article, the effect of size-dependent on the buckling and vibration analysis of functionally graded (FG) double-layer boron nitride plate based on classical plate theory (CPT) under electro-thermo-mechanical loadings which is surrounded by elastic foundation is examined. This subject is developed using modified couple stress theory. Using Hamilton's principle, the governing equations of...

BACKGROUND Routine laboratory monitoring is part of the basic care package offered to people living with the Human Immunodeficiency Virus (PLHIV). This paper aims to identify the proportion of PLHIVs with clinical and immunological failure who are virologically suppressed and risk being misclassified as treatment failures. METHODS A retrospective analysis of patient viral load data collected ...

While a core function of the working memory (WM) system is the active maintenance of behaviorally relevant sensory representations, it is also critical that distracting stimuli are appropriately ignored. We used functional magnetic resonance imaging to examine the role of domain-general WM resources in the top-down attentional modulation of task-relevant and irrelevant visual representations. I...

OBJECTIVES Many paediatric antiretroviral therapy (ART) programmes in Southern Africa rely on CD4⁺ to monitor ART. We assessed the benefit of replacing CD4⁺ by viral load monitoring. DESIGN A mathematical modelling study. METHODS A simulation model of HIV progression over 5 years in children on ART, parameterized by data from seven South African cohorts. We simulated treatment programmes wi...