Complex formation between Azotobacter vinelandii flavodoxin and horse cytochrome c has been demonstrated through cross-linking studies with dimethyl suberimidate, dimethyl adipimidate, 1-ethyl-3-(3-di-methylaminopropyl)carbodiimide, and dimethyl-3,3'-dithiobispropionimidate. Essentially quantitative cross-linking of cytochrome c and flavodoxin was observed at low ionic strengths with the carbod...

We read with interest the editorial entitled “Corneal Cross-linking (CXL): Standardizing Terminology and Protocol Nomenclature.”1 We would like to clarify that we recommended the use of the term “corneal crosslinking” in a previous publication.2 For the sake of completeness, a comprehensive bibliography supporting this claim is added here for the journal’s readers.3-6 In the same editorial, we ...

Objective: to present corneal collagen corsslinking techniques. Corneal collagen cross-linking (CXL) is a procedure used to slow down or arrest the progression of keratoconus in order to avoid or, at least delay the necessity of keratoplasty. CXL means photopolimerisation of the stromal fibrillar tissue, in order to increase their stiffness and resistance to the corneal ectasia. CXL is a proces...

PURPOSE To review cross-linking the cornea using riboflavin and ultraviolet A light, which has been widely adopted, refined and applied in a range of corneal surgeries and pathologies where the strength of the cornea might be compromised. RECENT FINDINGS A large number of clinical trials have been carried out, most of which have demonstrated that standard cross-linking is a successful method ...

A major challenge in Entity Linking (EL) is making effective use of contextual information to disambiguate mentions to Wikipedia that might refer to different entities in different contexts. The problem exacerbates with cross-lingual EL which involves linking mentions written in non-English documents to entries in the English Wikipedia: to compare textual clues across languages we need to compu...

Riboflavin-induced ultraviolet light (UV) cross linking has received a significant amount of attention in recent years. It is currently approved in Europe as a treatment for keratoconus and is also being used for other corneal disorders. The goal of this paper is to review in detail seminal papers and studies that have been done to support cross linking as a safe and effective treatment for pat...

We describe an algorithm and implementation of dynamic linking that allows one user process to link a program in another address space without compromising the security of the other address space and without requiring the linking process to enter kernel mode. The same technique can also be used to load program code into an existing address space, e.g., for debugging or other purposes. The imple...

combined oxidase/peroxidase that does the cross-linking, the cuticle separates into distinct layers, resulting in translucent worms that often suffer from massive blisters and defective movement. The clue that the cross-linking enzyme (called Duox for Dual Oxidase) might exist came from studies of phagocyte NADPH-oxidase. The latter enzyme generates bursts of superoxide to effect killing of eng...

The interaction of fibrinogen and fibronectin with hepatocytes has been dissociated into distinct binding and cross-linking steps. Binding and cross-linking of 125I-labeled ligands were both decreased by transglutaminase inhibitors, but not by heparin or hirudin. Transglutaminase activity was manifest by Ca2+-dependent incorporation of [14C]putrescine into cells. Preferential cross-linking of f...

Mesostructured silica films were formed from cross-linked poly(d8-styrene-block-2-vinylpyridine) (dPS-b-P2VP) diblock copolymer template films by swelling with silica precursor solutions. The mesoscopic and macroscopic morphologies of the resulting materials depended strongly on the extent of P2VP cross-linking. Without cross-linking, extensive rearrangement of the initial 2D hexagonal arrangem...