Although there have been substantial advances in the prevention and management of cardiovascular disease (CVD) and its complications, a new player and concept has entered the scene, namely an association between CVD and cancer. There were two alerting signals to this remarkable coupling. On the one hand, disconcerting evidence has been provided that suggests that the use of angiotensin receptor...

OBJECTIVE To evaluate the benefits and harms of aspirin for the primary prevention of CVD and determine whether the effects vary by sex and diabetes status. METHODS We searched Medline, Embase, and Cochrane databases for randomized controlled trials comparing the effects of aspirin with placebo or control in people with no pre-existing CVD. Two investigators independently extracted data and a...

BACKGROUND Vitamin and mineral supplements are commonly used to prevent chronic diseases. PURPOSE To systematically review evidence for the benefit and harms of vitamin and mineral supplements in community-dwelling, nutrient-sufficient adults for the primary prevention of cardiovascular disease (CVD) and cancer. DATA SOURCES MEDLINE, Embase, Cochrane Central Register of Controlled Trials, C...

Prediabetes, covering individuals with impaired fasting glycemia, impaired glucose tolerance, or high-risk HbA1c levels, is associated with a ∼20 % increased risk of developing cardiovascular disease (CVD) compared with normoglycemic individuals. It is well-known that lifestyle or pharmacologic interventions can prevent diabetes in prediabetic people; however, the evidence is less clear regardi...

OBJECTIVE The objective of this study was to describe French primary care physicians' beliefs about cardiovascular disease (CVD) risk factors and best practices for managing CVD. METHODS This study comprised a purposive convenience sample of 656 primary care physicians in France, recruited from contacts made through the French Society of General Medicine. We compiled the physicians' responses...

The burden of cardiovascular diseases (CVDs) has been steadily rising over the past decades, with an over 40% increase globally. Efforts in primary and secondary prevention of CVD and its associated risk factors are required to mitigate this epidemic. One of the chief risk factors contributing to the CVD burden is hypertension, as it is a significant contributor to CVD-related morbidity and mor...

Background The challenge of the primary prevention of cardiovascular disease (CVD) is to identify patients who would benefit from treatment with statins. Statins are currently prescribed to many patients, even those at a low 10-year risk of CVD. These latter patients may not be eligible for statins according to current guidelines. Design This study investigated the prescription of guideline-con...

OBJECTIVE To describe the prevalence of statin utilisation by people aged over 50 years in Ireland and the factors associated with the likelihood of using a statin, focusing particularly on those using statins for primary prevention of cardiovascular disease (CVD). METHODS This is a cross-sectional analysis of cardiovascular risk and sociodemographic factors associated with statin utilisation...

The American Heart Association (AHA) Nutrition Committee developed a behavioral roundtable to address cardiovascular disease (CVD) disparities, with a focus on the primary prevention of obesity. This roundtable considered the preventable differences in the indicators of health of different population groups, often defined by race, ethnicity, sex, educational level, socioeconomic status, and geo...