BACKGROUND AND PURPOSE A growing amount of evidence suggests that infectious and inflammatory processes may be involved in the initiation of arteriosclerosis, but the mechanisms are conceivably multifactorial and complex. Two European groups have recently demonstrated that a C(-260)-->T polymorphism in the promoter of the CD14 lipopolysaccharide receptor may be a risk factor for coronary artery...

MicroRNAs (miRNA) are considered to be potential therapeutic targets for the treatment of various cardiovascular diseases (CVDs). To understand the underlying mechanism of miRNAs and target genes associated with CVD, deep sequencing of blood samples from three patients with CVD and three controls was performed using the Illumina HiSeq 2000 system. The results of the present study revealed that ...

OBJECTIVE To inform potential pathophysiological mechanisms of air pollution effects on cardiovascular disease (CVD), we investigated short-term associations between ambient air pollution and a range of cardiovascular events from three national databases in England and Wales. METHODS Using a time-stratified case-crossover design, over 400,000 myocardial infarction (MI) events from the Myocard...

Inflammatory processes play a pivotal role in the pathogenesis of atherosclerosis and mediate many of the stages of atheroma development from initial leukocyte recruitment to eventual rupture of the unstable atherosclerotic plaque. C-reactive protein (CRP), an acute phase reactant that reflects different degree of inflammation, has been indicated an independent risk factor in a variety of cardi...

The wet-chemical synthesis of hollow graphitic spheres, a highly defined model catalyst support for electrocatalytic processes, is laborious and not scalable, which hampers potential applications. Here, we present insights into the chemical vapor deposition (CVD) ferrocene as simple, scalable method to synthesize spheres (HGScvd). During CVD process, iron carbon are embedded in pores mesoporous...

Stress- and inflammation-induced growth differentiation factor-15 (GDF-15) is proposed as a biomarker for mortality disease progression in patients with atherosclerosis and/or cardiovascular (CVD). The development of atherosclerotic lesions depends, among other factors, on inflammatory processes, oxidative stress, impaired lipid homeostasis. As consequence, activation dysfunction endothelial ce...

germanium nanowires (genws) were synthesized using chemical vapor deposition (cvd) based on vapor–liquid–solid (vls) mechanism with au nanoparticles as catalyst and germanium tetrachloride (gecl4) as a precursor of germanium. au catalysts were deposited on silicon wafer as a thin film, firstly by sputtering technique and secondly by submerging the silicon substrates in au colloidal solution, wh...

this paper discusses the use of box behnken design (bbd) approach to plan the experiments for turning the yield of cvd, thickness and layer number of graphene sheets with an overall objective of optimizing the process to provide higher graphene production volume, fewer layers and thinness structure of graphene. bbd is having the maximum efficiency for an experiment involving four factors such a...