نتایج جستجو برای: cxcl5

تعداد نتایج: 442  

Journal: :Proceedings of the American Thoracic Society 2006
Alberto Papi Fabrizio Luppi Francesca Franco Leonardo M Fabbri

Smokers with stable chronic obstructive pulmonary disease have a chronic inflammation of the entire tracheobronchial tree characterized by an increased number of macrophages and CD8 T lymphocytes in the airway wall and of neutrophils in the airway lumen. Exacerbations of chronic obstructive pulmonary disease are considered to reflect worsening of the underlying chronic inflammation of the airwa...

Journal: :American journal of physiology. Cell physiology 2006
Pascal J Lafontant Alan R Burns Elizabeth Donnachie Sandra B Haudek C Wayne Smith Mark L Entman

Ischemia-reperfusion injury in the heart is characterized by marked infiltration of neutrophils in the myocardial interstitial space. Studies in human, canine, and murine models have revealed oncostatin M (OSM) expression in infiltrating leukocytes. In an effort to assess possible roles of OSM in the myocardium, we used cardiac fibroblasts (mCFs) isolated from adult mouse heart to determine whe...

Journal: :Cancer discovery 2011
Sergey V Novitskiy Michael W Pickup Agnieszka E Gorska Philip Owens Anna Chytil Mary Aakre Huiyun Wu Yu Shyr Harold L Moses

We report that IL-17 significantly increases the secretion of CXCL1 and CXCL5 from mammary carcinoma cells, which is downregulated by TGF-β through the type II TGF-β receptor (TβRII). Carcinoma cells with conditional knockout of TβRII (Tgfbr2(KO)) have enhanced sensitivity to IL-17a in the stimulation of chemokine secretion. During polyoma middle T (PyMT) induced tumor progression, levels of Th...

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