Introduction and aim. The association between periodontitis (PD) rheumatoid arthritis (RA) has been analyzed described in literature. Periodontal pathogens, such as “Porphyromonas gingivalis” “Aggregatibacter actinomycetemcomitans” are pointed the common factors for both diseases. In this work we demonstrate that treatment of dental oral diseases is an unconditional requirement patients with RA...

Excretory/secretory products (ES), collected from in vitro cultures of muscle larvae (L1) of Trichinella spiralis (Owen, 1835) were examined for the presence of proteolytic enzymes. Several discrete proteinases in the size range of 25-55 kDa were identified by substrate gel electrophoresis and were characterised according to pH optima, substrate specificity and inhibitor sensitivity using azoca...

The Sunn pest, Eurygaster integriceps Puton (Heteroptera: Scutelleridae), is one of the most important pests of wheat and causes considerable damage to this valuable crop annually. Digestive proteinase activity of adult insects was investigated using general and specific substrates and inhibitors. Proteolytic activity was low when the common conventional substrates, azoalbumin, azocasein and he...

The mechanisms of gelation, proteinase effects on gel softening and the nature of changes associated with surimi quality are complex. Based on the results thus far studied, this review will focus on the proteinases/inhibitors and transglutaminase (TGase and MTGase) effects on the quality of surimi. Seafood industry might be interested in how to prevent the deterioration of protein gels and cons...

The reactions of papain (EC 3.4.22.2) with substrate-derived diazomethyl ketones reported by Leary, Larsen, Watanabe & Shaw [Biochemistry (1977) 16, 5857--5861] are unusual in that (i) these reagents fail to react with low-molecular-weight thiols and (ii) the rate of reaction with the papain thiol group does not decrease to near-zero values across a pKa of 4 as the pH is decreased. Existing dat...

A vacuolar cysteine proteinase, designated SH-EP, is expressed in the cotyledon of germinated Vigna mungo seeds and is responsible for the degradation of storage proteins. SH-EP is a characteristic vacuolar proteinase possessing a COOH-terminal endoplasmic reticulum (ER) retention sequence, KDEL. In this work, immunocytochemical analysis of the cotyledon cells of germinated V. mungo seeds was p...