Biomonitoring of pollutants and their metabolites and derivatives using biofluids provides new opportunities for spatiotemporal assessment of human risks to environmental exposures. Perfluorinated compounds (PFCs) have been used widely in industry and pose significant environmental concerns due to their stability and bioaccumulation in humans and animals. However, current methods for extraction...

There are numerous programs ongoing to analyze environmental exposure of humans to xenobiotic chemicals via biomonitoring measurements (e.g.: EU ESBIO, COPHES; US CDC NHANES; Canadian Health Measures Survey). The goal of these projects is to determine relative trends in exposure to chemicals, across time and subpopulations. Due to the lack of data, there is often little information correlating ...

The “European Human Biomonitoring Initiative” (HBM4EU) derives human biomonitoring guidance values (HBM-GVs) for the general population (HBM-GVGenPop) and/or occupationally exposed adults (HBM-GVWorker) several priority substances and substance groups as identified by policy makers, scientists stakeholders at EU national level, including bisphenol A (BPA). exposure to BPA is widespread of parti...

background: chromosome abnormality (ca) including sex chromosomes abnormality (scas) is one of the most important causes of disordered sexual development and infertility. scas formed by numerical or structural alteration in x and y chromosomes, are the most frequently ca encountered at both prenatal diagnosis and at birth. objective: this study describes cytogenetic findings of cases suspected ...

The use of human samples to assess environmental exposure and uptake of chemicals is more than an analytical exercise and requires consideration of the utility and interpretation of data as well as due consideration of ethical issues. These aspects are inextricably linked.In 2004 the EC expressed its commitment to the development of a harmonised approach to human biomonitoring (HBM) by includin...

In this issue of Environmental Health Perspectives (EHP), Schecter et al. (2011) report levels of poly brominated diphenyl ether (PBDE) flame retardants in butter purchased from retail stores. Although the investigators found prevalent levels of PBDEs in butter, they report that one sample had inordinately high levels of octa-, nona-, and deca-BDE con-geners, likely from its highly contaminated...

The active biomonitoring (ABM) approach was investigated using species of indigenous (from a pristine site) and transplanted (to a polluted area) fish Carassius auratus as an indicator organism of water/sediment pollution in Taihu Lake, a highly urbanized and industrialized area. The biotransformation enzymes 7-ethoxyresorufin-O-deethylase (EROD), reduced glutathione (GSH) content, catalase act...

We reviewed literature reporting both total and methylmercury from biota from Acadia National Park, Maine, USA. Our review of existing data indicates that 1) mercury contamination is widespread throughout the Park's various aquatic ecosystems; 2) mercury pollution likely represents a moderate to high risk to biota inhabiting the Park; and 3) biota at all trophic levels possess elevated concentr...

In this study, avoidance behavior of the freshwater cladoceran Daphnia magna Straus was used as indicator to assess the early stress of accidental organophosphorus pesticide (OP) contamination. The movement behavior was detected by a multi-species biomonitoring system. There was obvious concentration–response relationship between the OP stress and the behavioral response even at sublethal expos...