نتایج جستجو برای: cytopenia

تعداد نتایج: 953  

Journal: :Indian Journal of Hematology and Blood Transfusion 2014

Journal: :Journal of Bangladesh College of Physicians and Surgeons 2022

Introduction: The outbreak of Coronavirus Disease 2019 (COVID-19) caused by Severe Acute Respiratory Syndrome 2 (SARS-CoV-2) has posed great threat to human health. T cells play a critical role in antiviral immunity but their numbers and functional state COVID-19 patients remain largely unclear. present study was carried out at Armed Forces Institute Pathology (AFIP), Dhaka assess the degree cy...

Journal: :Blood 2011
Masatoshi Takagi Kunihiro Shinoda Jinhua Piao Noriko Mitsuiki Mari Takagi Kazuyuki Matsuda Hideki Muramatsu Sayoko Doisaki Masayuki Nagasawa Tomohiro Morio Yoshihito Kasahara Kenichi Koike Seiji Kojima Akira Takao Shuki Mizutani

Autoimmune lymphoproliferative syndrome (ALPS) is classically defined as a disease with defective FAS-mediated apoptosis (type I-III). Germline NRAS mutation was recently identified in type IV ALPS. We report 2 cases with ALPS-like disease with somatic KRAS mutation. Both cases were characterized by prominent autoimmune cytopenia and lymphoadenopathy/splenomegaly. These patients did not satisfy...

Journal: :JPMA. The Journal of the Pakistan Medical Association 1994
T S Shamsi K Z Hashmi

Hairy cell leukaemia is a chronic B cell disorder which runs an an indolent but progressive course characterized by cytopenia, recurrent infections and splenomegaly. The hallmark of this disease is the presence of cells with filiform cytoplasmic surface projections in peripheral blood and/or bone marrow. In recent years the introduction of new chemotherapeutic agents has revolutionized the trea...

2013
Kwang Il Ko Mi Jung Lee Fa Mee Doh Hyang Mo Koo Chan Ho Kim Dong Ho Shin Hyung Jung Oh Seung Hyeok Han Shin-Wook Kang Kyu Hun Choi Tae-Hyun Yoo

A 74-year-old woman presented with edema in the lower extremities. Laboratory tests revealed anemia, thrombocytopenia, hypoalbuminemia, hypercholesterolemia, and nephrotic-range proteinuria. Myelodysplastic syndrome-refractory cytopenia with multilineage dysplasia (MDS-RCMD) was confirmed by bone marrow biopsy. Renal biopsy demonstrated membranous glomerulonephritis (MGN), stage I. Based on the...

Journal: :JAMA oncology 2015
Mouhab Ayas

Aplastic anemia is a condition in which the hematopoietic stem cells fail to function adequately leading to peripheral pancytopenia. When the cytopenia is severe, patients require intensive support with blood products and broad spectrum antibiotics, and without definitive treatment, most will eventually die of infections or bleeding. Over the past 4 decades, however, these once uniformly fatal ...

Journal: :Pediatric hematology and oncology 2012
Bibi Shahin Shamsian Nima Rezaei Samin Alavi Mona Hedayat Ali Amin Asnafi Zahra Pourpak Atoosa Gharib Farzaneh Jadali Mohammad Taghi Arzanian

Hemophagocytic lymphohistiocytosis (HLH) is a rare condition characterized by fever, hepatosplenomegaly, and cytopenia, and widespread accumulation of lymphocytes and histiocytes, sometimes with hemophagocytosis, primarily involving the spleen, lymph nodes, bone marrow, and liver. HLH can either occur sporadically (secondary HLH) or as part of a familial syndrome (primary HLH), including famili...

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