نتایج جستجو برای: cytoscape

تعداد نتایج: 948  

2016
Jamie Soul Sara L. Dunn Tim E. Hardingham Ray P. Boot-Handford Jean-Marc Schwartz

PhenomeScape is a Cytoscape app which provides easy access to the PhenomeExpress algorithm to interpret gene expression data. PhenomeExpress integrates protein interaction networks with known phenotype to gene associations to find active sub-networks enriched in differentially expressed genes. It also incorporates cross-species phenotypes and associations to include results from animal models o...

Journal: :Journal of Bioinformatics and Computational Biology 2013

2016
Tanja Muetze Ivan H. Goenawan Heather L. Wiencko Manuel Bernal-Llinares Kenneth Bryan David J. Lynn Christopher K. Tuggle Haibo Liu Sandra Orchard Pablo Porras Millán Tanja Muetze

Highly connected nodes (hubs) in biological networks are topologically important to the structure of the network and have also been shown to be preferentially associated with a range of phenotypes of interest. The relative importance of a hub node, however, can change depending on the biological context. Here, we report a Cytoscape app, the Contextual Hub Analysis Tool (CHAT), which enables use...

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