Cellular FLICE (FADD-like IL-1beta-converting enzyme)-inhibitory protein (c-FLIP) is a major resistance factor and critical anti-apoptotic regulator that inhibits tumor necrosis factor-alpha (TNF-alpha), Fas-L, and TNF-related apoptosis-inducing ligand (TRAIL)-induced apoptosis as well as chemotherapy-triggered apoptosis in malignant cells. c-FLIP is expressed as long (c-FLIP(L)), short (c-FLIP...

Spectroscopic measurements have been made of the nitric oxide and water vapor concentrations in the stratosphere at an altitude of 28 kilometers. The measurements, carried out in situ with the use of a spin flip Raman laser, represent the first accurate determination of nitric oxide as a function of time (as the sun rose) from about 6: 30 to 14: 00 C. D. T.

We consider spin-flip dynamics of configurations in $\{-1,1\}^{\mathbb{Z}^d}$, and study the time evolution concentration inequalities. For "weakly interacting" we show that Gaussian bound is conserved course it satisfied by unique stationary Gibbs measure. Next that, for a general class translation-invariant dynamics, impossible to evolve finite from low-temperature state towards measure satis...

The mTOR positively regulates cell proliferation and survival through forming 2 complexes with raptor (mTOR complex 1; mTORC1) or rictor (mTOR complex 2; mTORC2). Compared with the mTORC1, relatively little is known about the biologic functions of mTORC2. This study focuses on addressing whether mTORC2 regulates apoptosis, particularly induced by TRAIL (TNFSF10). Using the mTOR kinase inhibitor...

Motivated by recent progress in cold-atom experiments, we analyze the $\mathrm{SU}(N$) Fermi-Hubbard model on a $d$-dimensional hypercubic lattice with two-body loss. By focusing states near ferromagnetic steady states, obtain Liouvillian gap closed form for any $d$ and $N$. We also investigate dynamics of initial state single spin flip both analytically numerically. In particular, show that, d...

We recently reported that a functional ligand-binding site of an alpha-amino-5-methyl-3-hydroxy-4-isoxazole propionate (AMPA)-selective glutamate receptor (GluR)-D subunit can be expressed in insect cells as a soluble, N-glycosylated fusion protein consisting of two segments (S1 and S2) that are related by amino acid sequence to bacterial periplasmic binding proteins (Kuusinen, A., Arvola, M., ...

In digital VLSI system the clock distribution network and flip flops are most power consuming components. The reduction of power consumption by clock distribution networks & flip flop makes the total VLSI system as low power VLSI system. In the earlier VLSI system design, different power consumption methods are followed to design the various flip-flops .The SABFF(sense amplifier based flip flop...

The enzyme system was used to mimic the D-flip-flop memory unit. The reversible conversion of NAD(+) and NADH cofactors was used to encode the states of the memory unit, while a mixture of inhibitors was used as the Clock input and the substrates were used as the Data input.