نتایج جستجو برای: d2 law

تعداد نتایج: 182958  

Journal: :American journal of physiology. Endocrinology and metabolism 2005
Robin P Peeters Annewieke W van den Beld Hayat Attalki Hans van Toor Yolanda B de Rijke George G J M Kuiper Steven W J Lamberts Joop A M J L Janssen Andre G Uitterlinden Theo J Visser

Type II deiodinase (D2) is important in the regulation of local thyroid hormone bioactivity in certain tissues. D2 in skeletal muscle may also play a role in serum triiodothyronine (T(3)) production. In this study, we identified a polymorphism in the 5'-UTR of the D2 gene (D2-ORFa-Gly3Asp). We investigated the association of D2-ORFa-Gly3Asp, and of the previously identified D2-Thr92Ala polymorp...

J. Zhao W. Duan Y. Shi, Zh. Yu

A field experiment was conducted to examine the effects of different depths ofnitrogen (N) fertiliser placements on N accumulation, remobilisation and NO3−-Ncontent in soil of rainfed wheat. Nitrogen was applied on the surface (D1) and inthe 10 cm (D2), 20 cm (D3) and 30 cm (D4) soil layers from 2010 to 2012.Compared with D1 and D2, D3 and D4 treatments obtained significant higher Ndistribution...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1994
S R Sesack C Aoki V M Pickel

Potential cellular substrates for functions ascribed to the dopamine D2 receptor were examined in rat brain using immunoperoxidase for localization of a D2 receptor peptide and immunogold staining for the catecholamine biosynthetic enzyme tyrosine hydroxylase (TH). Specificity of the rat polyclonal antiserum, raised against a 15 amino acid fragment from the third intracellular loop of the D2 re...

Introduction: The hippocampus (HIP), the primary brain structure related to learning and memory, receives sparse but comprehensive dopamine innervations and contains dopamine D1/D2-like receptors. It is demonstrated that dopamine receptors in dentate gyrus (DG) region of HIP have a remarkable function in spatial reward processing. Much less is known about the involvement of HIP and its D1...

Journal: :The Journal of clinical investigation 1996
D Salvatore H Tu J W Harney P R Larsen

Type 2 iodothyronine deiodinase (D2) is a recently cloned selenodeiodinase thought to provide intracellular 3,5,3' triiodothyronine (T3) to a restricted group of tissues. We report here the presence of D2 mRNA in human thyroid at levels 50-150-fold higher than in placenta. Surprisingly, while type 1 deiodinase (D1) is known to be present in human thyroid, D2 has not been evaluated previously. D...

Journal: :Endocrinology 2006
Marcelo A Christoffolete Rogério Ribeiro Praful Singru Csaba Fekete Wagner S da Silva David F Gordon Stephen A Huang Alessandra Crescenzi John W Harney E Chester Ridgway P Reed Larsen Ronald M Lechan Antonio C Bianco

T(4), the main product of thyroid secretion, is a critical signal in plasma that mediates the TSH-negative feedback mechanism. As a prohormone, T(4) must be converted to T(3) to acquire biological activity; thus, type 2 iodothyronine deiodinase (D2) is expected to play a critical role in this feedback mechanism. However, the mechanistic details of this pathway are still missing because, counter...

2007
K. Subramani

Solution: Yes; for instance consider the language L = {5}, i.e., the language containing a single element and the corresponding decision problem: D1: Does x ∈ L?. I can reduce an arbitrary decision problem D2 ∈ P to D1 using the reduction f , which is defined as follows: Given x as input to D2, f first checks in polynomial time, whether x ∈ D1. If x is a “yes” instance of D2, f(x) = 5; otherwis...

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