Interpretation of an earlier published infrared spectrum of Mycobacterium smegmatis lipids with receptor site activity for D4 phage led us to the inference that the active substance is very likely a mycoside C. This hypothesis was confirmed: the well-characterized mycosides C(s) and C(1217) elaborated by the heterologous strains M. scrofulaceum and Mycobacterium species 1217, respectively, are ...

A synthetic mimic of mussel adhesive protein, dopamine-modified four-armed poly(ethylene glycol) (PEG-D4), was combined with a synthetic nanosilicate, Laponite (Na(0.7+)(Mg5.5Li0.3Si8)O20(OH)4)(0.7-)), to form an injectable naoncomposite tissue adhesive hydrogel. Incorporation of up to 2 wt % Laponite significantly reduced the cure time while enhancing the bulk mechanical and adhesive propertie...

Apomorphine has been used as a pharmacological probe of dopaminergic receptors in a variety of central nervous system disorders. The utility of apomorphine as an agent for the treatment of erectile dysfunction has also been demonstrated clinically. Apomorphine is a nonselective dopaminergic receptor agonist with potent binding affinity (Ki) of 101, 32, 26, 2.6, and 10 nM for D1, D2, D3, D4, and...

Let p, q, r, s be polynomials with integer coefficients. This paper presents a fast method, using very little temporary storage, to find all small integers (a, b, c, d) satisfying p(a)+q(b) = r(c)+s(d). Numerical results include all small solutions to a4 + b4 +c4 = d4; all small solutions to a4 + b4 = c4 +d4; and the smallest positive integer that can be written in 5 ways as a sum of two coprim...

Let p, q, r, s be polynomials with integer coefficients. This paper presents a fast method, using very little temporary storage, to find all small integers (a, b, c, d) satisfying p(a)+q(b) = r(c)+s(d). Numerical results include all small solutions to a4 + b4 +c4 = d4; all small solutions to a4 + b4 = c4 +d4; and the smallest positive integer that can be written in 5 ways as a sum of two coprim...

In this study, the various core sizes of manganese ferrite nanoparticles(MnFe2O4) conjugated with D4 peptide (MnFe2O4-PEG-D4) were synthesized. The highrelaxivityMnFe2O4 nanoparticles were obtained by thermal decomposition of Iron acetylacetonate and manganese acetylacetonate in hydrophobic solution athigh boiling process. The surface ofMnFe2O4 nanoparticles were coated ...

Primary spinal non-Hodgkin's lymphoma is extremely rare, and the occurrence of spinal dumbbell-shaped lymphoma is exceptional. We present a case of primary spinal dumbbell-shaped lymphoma to clarify the diagnosis and the management of these lesions. A 45-year-old man presented with sensory symptoms for 8 months. Magnetic resonance imaging of the thoracic spine demonstrated a dumbbell-shaped les...

We construct two abelian extensions of Ω3G, one by the abelian group Map(D4 0G,U(1)) and the other by Map((D )0G,U(1)), where D4 0G is the group of mappings from the unit four-disc D 4 to G = SU(N), N ≥ 3, that are equal to 1 on the boundary S3, and the prime indicates the opposite orientation of D4. They are homotopically equivalent to a U(1) principal bundle over Ω3G and the associated line b...

We consider aspects of instanton dynamics in the large-N limit using the AdS/CFT duality for D0/D4 bound states. In the supergravity picture of wrapped D0-brane worldlines on D4-branes, we find the single-instanton measure and discuss its dependence on compactification finite-size effects, as well as its matching to perturbative results. In the non-supersymmetric case, the same dynamical effect...

This pilot study compared second- and fourth-year dental students' perceived values of newly implemented clinical leadership experiences (CLEs) at one U.S. dental school during the 2012-13 academic year. In the CLEs, fourth-year (D4) students mentored second-year (D2) dental students during faculty-supervised patient treatment. The two cohorts' perceived value of the experiences was measured wi...