BACKGROUND We reviewed systematically the results of genetic studies investigating associations between putative susceptibility genes for attention-deficit hyperactivity disorder (ADHD) and neuropsychological traits relevant for this disorder. METHODS We identified papers for review through the PubMed database. RESULTS Twenty-nine studies examined 10 genes (DRD4, DAT1, COMT, DBH, MAOA, DRD5...

BACKGROUND The study of gene-environment interactions (G × E) is one of the most promising strategies to uncover the origins of mental disorders. Replication of initial findings, however, is essential because there is a strong possibility of publication bias in the literature. In addition, there is a scarcity of research on the topic originated from low- and middle-income countries (LMIC). The ...

There is growing interest in understanding the neurobiological foundations of attention. To examine whether attentional processes in a change detection task are modulated by dopamine signalling, we investigated the influence of two polymorphisms, i.e. Val158Met (rs4680) in the catechol-O-methyl transferase (COMT) and a variable number of tandem repeats polymorphism (VNTR, rs28363170) in the dop...

BACKGROUND Currently, there is a sense that the spatial orienting of attention is related to genotypic variations in cholinergic genes but not to variations in dopaminergic genes. However, reexamination of associations with both cholinergic and dopaminergic genes is warranted because previous studies used endogenous rather than exogenous cues and costs and benefits were not analyzed separately....

AIMS It was investigated whether the allele A9 of the dopamine transporter gene (DAT1; SLC6A3) is associated with alcoholism, delirium tremens (DT), alcohol withdrawal seizures (AWS), or the daily alcohol intake. METHODS A group of 102 healthy subjects and 216 alcoholics, including 97 patients with a history of mild withdrawal symptoms, 65 with a history of AWS and 83 with a history of DT wer...

Background Use of Direct Antiglobulin test (DAT) in management neonatal hyperbilirubinemia is conflicting.Objective whether strength positive DAT predicts the need for phototherapy, duration phototherapy and major interventions.Methods We retrospectively collected data on all neonates with birth gestational age ≥32 weeks over six years (2014–2019). Data regarding blood group, clinical details w...