Abstract Objectives Data on consumption of tetracyclines, sulphonamides and trimethoprim, other antibacterials were collected from 30 EU/European Economic Area (EEA) countries over two decades. This article reviews temporal trends, seasonal variation, presence change-points changes in the composition main subgroups trimethoprim antibacterials. Methods For period 1997–2017, data tetracyclines (A...

BACKGROUND Metabolomics in human nutrition research is faced with the challenge that changes in metabolic profiles resulting from diet may be difficult to differentiate from normal physiologic variation. OBJECTIVE We assessed the extent of intra- and interindividual variation in normal human metabolic profiles and investigated the effect of standardizing diet on reducing variation. DESIGN U...