BACKGROUND In a structure-based virtual screening, the choice of the docking program is essential for the success of a hit identification. Benchmarks are meant to help in guiding this choice, especially when undertaken on a large variety of protein targets. Here, the performance of four popular virtual screening programs, Gold, Glide, Surflex and FlexX, is compared using the Directory of Useful...

This paper aims to offer an advanced assessment methodology for sustainable national energy-environment-economic efficiency strategies, based on an extended Data Envelopment Analysis (DEA). The use of novel efficiency-improving approaches based on DEA originates from the so-called Distance Friction Minimisation (DFM) method. To design a feasible improvement strategy for low-efficiency DMUs, we ...

COCO is a platform for Comparing Continuous Optimizers in a black-box setting. It aims at automatizing the tedious and repetitive task of benchmarking numerical optimization algorithms to the greatest possible extent. We present the rationals behind the development of the platform as a general proposition for a guideline towards better benchmarking. We detail underlying fundamental concepts of ...

The adaptive local hyperplane (ALH) algorithm is a very recently proposed classifier, which has been shown to perform better than many other benchmarking classifiers including support vector machine (SVM), K-nearest neighbor (KNN), linear discriminant analysis (LDA), and K-local hyperplane distance nearest neighbor (HKNN) algorithms. Although the ALH algorithm is well formulated and despite the...

Environmental performance assessments are often conducted using environmental indicators. Although these indicators provide a starting point for performance assessments, they do not provide guidelines that countries should follow to improve performance. This paper develops an enhanced Data Envelopment Analysis (DEA) model that provides a single summary measure of countries’ environmental perfor...

Reaching to a location in space is supported by a cortical network that operates in a variety of reference frames. Computational models and recent fMRI evidence suggest that this diversity originates from neuronal populations dynamically shifting between reference frames as a function of task demands and sensory modality. In this human fMRI study, we extend this framework to nonmanipulative gra...

Article history: Received 5 January 2014 Received in revised format 8 March 2014 Accepted 11 March 2014 Available online 12 March 2014 Measuring the relative efficiency of banking industry has been a popular subject among both practitioners and academicians. Data envelopment analysis (DEA) has been widely applied for different purposes. This paper presents an empirical investigation to measure ...

The car manufacturing industry, one of the largest energy consuming industries, has been making a considerable effort to improve its energy intensity by implementing energy efficiency programs, in many cases supported by government research or financial programs. While many car manufacturers claim that they have made substantial progress in energy efficiency improvement over the past years thro...

Reaching to a location in space is supported by a cortical network that operates in a variety of reference frames. Computational models and recent fMRI evidence suggest that this diversity originates from neuronal populations dynamically shifting between reference frames as a function of task demands and sensory modality. In this human fMRI study, we extend this framework to nonmanipulative gra...