Tetraarylpyrenes H1-H4 that typify molecular systems with orthogonal planes and lack hydrogen bonding functional groups were designed as new host systems with three distinct domains for guest inclusion. In particular, H2 and H4 hosts are found to include a variety of guest molecules. We have determined 42 crystal structures overall (i) to establish the importance of skeletal features of the hos...

Introduction Liver inflammatory response occurring after toxic chemicals injection, such as cisplatin, causes the aggravation in liver damage. Lycopene, a carotenoid, has previously been proven to possess antioxidant, antiinflammatory and antiapoptotic properties. This study objective was evaluate for first time protective effects of lycopene cisplatin-induced damage based on disturbances serum...

Shear-thinning fluids exhibit surprisingly rich behaviour. One example is the Kaye effect which occurs when a thin stream of a solution of polyisobutylene in decalin is poured into a dish of the fluid. As pouring proceeds, a small stream of liquid occasionally leaps upward from the heap. This surprising effect, which lasts only a second or so, is named after its first observer, Kaye, who could ...

Charge-carrier recombination dynamics after laser excitation are investigated by time-resolved microwave conductivity (TRMC) measurements of quantum-sized (Q-) TiO, , Fell'-doped Q-TiO, , ZnO and CdS, and several commercial bulk-sized TiO, samples. After pulsed laser excitation of charge carriers, holes that escape recombination react with sorbed trans-decalin within ns while the measured condu...

Neighbouring group participation is frequently used to control the stereoselectivity of chemical reactions. Herein, we investigate the use of neighbouring group participation for the synthesis of disaccharides incorporating the mycobacterial sugar methylthioxylose. A bicyclic thioglycoside was activated by methylation to generate a methylsulfonium group that would act both as the anomeric leavi...

Fusarisetin A (1) is a recently isolated natural product that displays an unprecedented chemical motif and remarkable bioactivities as a potent cancer migration inhibitor. We describe here our studies leading to an efficient and scalable total synthesis of 1. Essential to the strategy was the development of a new route for the formation of a trans-decalin moiety of this compound and the applica...