Osteoarthritis (OA) is one of the most common forms of degenerative joint disease and a major cause of pain and disability affecting the aging population. It is estimated that more than 20 million Americans and 35 to 40 million Europeans suffer from OA. Analgesics and non-steroidal anti-inflammatory drugs (NSAIDs) are the only therapeutic treatment options for OA. Effective pharmacotherapy for ...

Osteoarthritis (OA), also known as degenerative joint disease or osteoarthrosis, is the most common form of arthritis. OA occurs when cartilage in the joints wears down over time. We used the GSE1919 series to identify potential genes that correlated to OA. The aim of our study was to obtain a molecular signature of OA through the regulation netwo...

Falls are a major concern in the elderly population with chronic joint disease. To compare muscular function and functional mobility among older women with knee osteoarthritis with and without a history of falls, 15 elderly women with a history of falls (74.20 +/- 4.46 years) and 15 without a history of falls (71.73 +/- 4.73 years) were studied. Muscular function, at the angular speed of 60, 12...

BACKGROUND AND PURPOSE Of the various physical interventions used to relieve the symptoms of osteoarthritis (OA), a common degenerative joint disease causing considerable pain and disability, low power laser therapy has been reported to be extremely successful in Russia and Eastern Europe. METHOD Although the overall number of studies was small, this literature review and analysis highlights ...

Objectives: Estimating the possible causes of arthropathies in patients with type 2 diabetes mellitus attending outpatient clinics of internal medicine department at Menoufia university hospital. Background: Diabetes mellitus (DM) is a chronic disease and has become one of the main threats to human health in recent decades. Diabetes worldwide was estimated at between 151 million and 171 million...

The relationship between the bone mineral density (BMD) and Charcot arthropathy is unclear. Prospectively, 55 consecutive diabetic patients presenting with a Charcot arthropathy of the foot or ankle were classified as having a fracture, dislocation, or a combination fracture-dislocation pattern of initial destruction. In these groups we used dual-energy x-ray absorptiometry to compare the perip...

To prevent hemophilic arthropathy, prophylactic treatment of children with severe hemophilia should be started before joint damage has occurred. However, treatment is expensive, and the burden of regular venipunctures in young children is high. With the aim of providing information on starting prophylaxis on the basis of individual patient characteristics, the effect of postponing prophylaxis o...

We report a case of amyloid arthropathy in a patient with multiple myeloma. Amyloid arthropathy is a very rare condition that may be associated with multiple myeloma. It presented in our patient as soft tissue masses around joints and eroding into adjacent bones. We found it to be hypermetabolic on fused positron emission tomography and computed tomographic scanning.