نتایج جستجو برای: demyelinating disease
تعداد نتایج: 1495276 فیلتر نتایج به سال:
OBJECTIVES To investigate the nature and cause in eight black South African patients of a recurrent (multiphasic), remitting, and relapsing demyelinating disease of the CNS. METHODS The clinical and laboratory investigations and radiological manifestations of these patients were documented. RESULTS Each patient had two or more acute attacks of demyelinating disease affecting the CNS. The cl...
Demyelination in the central nervous system induced by neurovirulent strains of Mouse Hepatitis Virus (MHV) is mediated by the viral spike glycoprotein, but it is not clear whether the mechanism of this disease pathology involves direct viral infection of oligodendrocytes. Detailed studies of glial cell tropism of MHV are presented, demonstrating that direct MHV infection of oligodendrocytes di...
BACKGROUND Demyelinating polyneuropathy is a debilitating, poorly understood disease that can exist in acute (Guillain-Barré syndrome) or chronic forms. Interleukin-10 (IL-10), although traditionally considered an anti-inflammatory cytokine, has also been implicated in promoting abnormal angiogenesis in the eye and in the pathobiology of autoimmune diseases such as lupus and encephalomyelitis. ...
Multiple Sclerosis is a chronic inflammatory disease. It characterized by demyelinating lesions throughout the central nervous system. Patients suffering from multiple sclerosis constitute vulnerable population to coronavirus disease-2019. This review focuses on effects of disease-2019 relapse and symptom exacerbation in patients their treatment. highlights how blood-brain barrier may be compro...
Three patients fulfilled the diagnostic criteria for both multiple sclerosis and pseudotumor cerebri. Although coincidence is possible, intracranial hypertension may be a manifestation of demyelinating disease.
Autosomal recessive demyelinating Charcot-Marie-Tooth disease (CMT4), Dejerine-Sottas disease and congenital hypomyelinating neuropathy are variants of hereditary demyelinating neuropathy of infancy, a genetically heterogeneous group of disorders. To explore the spectrum of early-onset demyelinating neuropathies further, we studied the clinicopathological and genetic aspects of 20 patients born...
myelinating disease of the central nervous system (CNS) that takes a relapsing–remitting or a progressive course (reviewed in Refs 1,2). Its counterpart in the peripheral nervous system (PNS) is chronic inflammatory demyelinating polyradiculoneuropathy (CIDP) (reviewed in Ref. 3). In addition, there are acute, monophasic disorders, such as the inflammatory demyelinating polyradiculoneuropathy t...
Multiple sclerosis (MS) is the most common chronic inflammatory demyelinating disease of central nervous system (CNS). MS diagnosis and monitoring are mostly based on Magnetic Resonance Imaging (MRI). This study aims to compare a double inversion recovery MRI sequence with fluid-attenuated in Sclerosis brain. A was conducted 75 patients whose aged between 10 70 years who were having brain
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