BACKGROUND Previous studies have demonstrated that a number of HOX genes, a family of transcription factors with key roles in early development, are up-regulated in head and neck squamous cell carcinoma (HNSCC) and other cancers. The loci of several Homeobox (HOX) genes also contain microRNAs (miRs), including miR-196a. METHODS Global miR expression and expression of all 39 HOX genes in norma...

We investigate polyelectrolyte bridging interactions mediated by charged, flexible, polyelectrolyte chains between fixed cylindrical macroions of opposite charge in a two-dimensional hexagonal crystalline array. We show that in the asymptotic regime of small macroion density, the polyelectrolyte-mediated attraction is long range, falling off approximately linearly with the macroion array densit...

RNA quality control is a crucial step in guaranteeing integer nondegraded RNA and receiving meaningful results in gene expression profiling experiments, using micro-array, RT-qPCR (Reverse-Transcription quantitative PCR), or Next-Generation-Sequencing by RNA-Seq or small-RNA Seq. Therefore, assessment of RNA integrity and purity is very essential prior to gene expression analysis of sample RNA ...

Tendinopathy is often discovered late because the initial development of tendon pathology is asymptomatic. The aim of this study was to examine the potential role of mast cell involvement in early tendinopathy using a high-intensity uphill running (HIUR) exercise model. Twenty-four male Wistar rats were divided in two groups: running group (n = 12); sedentary control group (n = 12). The running...

This paper tries to determine an optimum condition for the flotation operation of the Alborz-Sharghi coal washing plant. For this purpose, a series of comprehensive experiments have been conducted on representative samples from feed of the flotation system of the plant. Four operational variables such as the collector dosage (Fuel oil), the frother dosages (MIBC), the pulp density percent and t...

The reliable quantification of ultraviolet (UV) radiation at the earth’s surface requires accurate measurements of spectral global solar UV irradiance in order to determine the UV exposure to human skin and to understand long-term trends in this parameter. Array spectroradiometers (ASRMs) are small, light, robust and cost-effective instruments, and are increasingly used for spectral irradiance ...

The first generation of epoch of reionization experiments have the potential to characterize the processes and history of reionization for redshifts 6 < z < 12 by observing the power spectrum of the redshifted 21 cm radiation. These power spectrum observations could also contribute to our knowledge of the underlying cosmology, particularly at redshifts before the effects of reionization strongl...