Most studies aimed at understanding the link between inflammation and cancer progression have focused on macrophages. In a recent study published in PLoS Biology, Toh B et al (2011) Mesenchymal transition and dissemination of cancer cells is driven by myeloid-derived suppressor cells infiltrating the primary tumorPLoS Biol9 e1001162, we show that a subset of granulocytic cells already known to ...

False discovery rate (FDR) control has become a standard technique in neuroimaging. Recent work has shown that a finer grained estimate of the FDR is obtained by estimating, at a specific value of the test statistic, the scaled ratio of the null density to the observed density of the test statistic. The method can be extended by allowing an external covariate, also measured on the points where ...

Myeloid derived suppressor cells (MDSCs) are defined in mice on the basis of CD11b and Gr-1 marker expression and the functional ability to inhibit T lymphocyte activation. Nevertheless the term 'heterogeneous' remains the first, informal feature commonly attributed to this population. It is clear that CD11b(+)Gr-1(+) cells are part of a myeloid macropopulation, which comprises at least two sub...

In this paper, we show that for a connected compact Lie group to be acceptable, it is necessary and sufficient its derived subgroup isomorphic direct product of the groups $${\text {SU}}(n)$$ , {Sp}}(n)$$ {SO}}(2n+1)$$ {G}}_2$$ {SO}}(4)$$ . We there are invariant functions on {SO}}_{4}({\mathbb {C}})^{2}$$ which not generated by 1-argument invariants, though {C}})$$ acceptable.

a group $g$ is called metahamiltonian if all its non-abelian subgroups are normal‎. ‎the aim of this paper is to provide an updated survey of research concerning certain classes of generalized metahamiltonian groups‎, ‎in various contexts‎, ‎and to prove some new results‎. ‎some open problems are listed‎.

Sequence analysis of a large number of clones derived from the carboxy-terminal one-third of the attachment (G) protein gene of subgroup A respiratory syncytial viruses revealed a region very prone to polymerase errors which resulted mainly in frameshifts because of the insertion or deletion of adenosine residues in some but not all runs of such residues. Such mutations were detected in 14% of ...

an algebraic construction for constant dimension subspace codes is called orbit code. it arises as the orbits under the action of a subgroup of the general linear group on subspaces in an ambient space. in particular orbit codes of a singer subgroup of the general linear group has investigated recently. in this paper, we consider the normalizer of a singer subgroup of the general linear group a...

We give efficient quantum algorithms for HIDDEN TRANSLATION and HIDDEN SUBGROUP in a large class of non-abelian groups including solvable groups of bounded exponent and of bounded derived series. Our algorithms are recursive. For the base case, we solve efficiently HIDDEN TRANSLATION in Z p , whenever p is a fixed prime. For the induction step, we introduce the problem ORBIT COSET generalizing ...

This paper gives some geometric applications of the derived McKay correspondence established by T.Bridgeland, A.King and M.Reid. Let G ⊂ SL(2,C) be a finite subgroup, and X be the moduli space of G-clusters. They showed that X gives a crepant resolution of the quotient C2/G, and X is derived equivalent to Gequivariant coherent sheaves on C2. In this paper, we apply it to compare Hilbert schemes...

This paper studies Emerton’s Jacquet module functor for locally analytic representations of p-adic reductive groups, introduced in [Eme06a]. When P is a parabolic subgroup whose Levi factor M is not commutative, we show that passing to an isotypical subspace for the derived subgroup ofM gives rise to essentially admissible locally analytic representations of the torus Z(M), which have a natural...