Wounds with full-thickness skin loss are commonly managed by skin grafting. In the absence of a graft, reepithelialization is imperfect and leads to increased scar formation. Biomaterials can alter wound healing so that it produces more regenerative tissue and fewer scars. This current study use the new chitosan based biomaterial in full-thickness wound with impaired healing on rat model. Wound...

Background Avoiding delay in the surgical management of pectoralis major (PM) ruptures optimizes outcomes. However, this is not always possible, and when a tear becomes chronic or when a subacute tear has poor tissue quality, a graft can facilitate reconstruction. Purpose The primary aim was to evaluate the clinical outcomes of PM reconstruction with dermal allograft augmentation for chronic ...

OBJECTIVE The purpose of this 16-week, multicenter, randomized, controlled trial was to assess the healed ulcer rate of a human acellular dermal matrix, DermACELL, compared with conventional care and a second acellular dermal matrix, Graftjacket, in the treatment of full-thickness diabetic foot ulcers. METHODS One hundred sixty-eight patients were randomized into DermACELL, conventional care,...

AIMS To prospectively evaluate the reliability and efficacy of a new treatment for the reconstruction of the lacrimal duct using a new histo-engineered material, xenogeneic (bovine) acellular dermal matrix. METHOD Five patients (five eyes) with partial or total absence of the lacrimal duct were included in the study. Four patients (four eyes) suffered from traumatic injuries to the lacrimal d...

Gingival recession is one of the most common soft tissue problems, especially when it hinders the esthetics of a patient. Gingival recession can further lead to root caries, sensitivity, and difficulty in plaque control. Moreover, exposed roots are prone to abrasion and erosion. Periodontal plastic surgery is one of the emerging fields, which helps to meet such soft tissue problems. Currently, ...

1 Sociedade Brasileira de Cirurgia Plástica, Rio de Janeiro, RJ, Brazil. 2 Hospital dos Servidores do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil. 3 Sociedade Brasileira de Microcirurgia Reconstrutiva, Rio de Janeiro, RJ, Brazil. In more-distal amputations of the fingertips, microsurgical replantation is not feasible. For these cases, composite graft provides the best functional and ae...

Sixteen clinically healthy New Zealand white rabbits of either sex were divided into 2 equal groups (I and II) of 8 animals each. Under thiopental sodium (2.5%) anaesthesia a 2 x 3 cm full-thickness abdominal wall defect in the mid-ventral abdominal wall was created and repaired with an acellular dermal graft (ADG) in all the animals of group I (test group). In animals of group II (control grou...