T is an active principle of Nigella sativa (N. sativa), which is a member of the Ranunculaceae family of plants. Several active ingredients have been isolated from the seeds of N. sativa, and many pharmacological effects, such as anti-bacterial, antiparasitic, anti-cancer, and anti-inflammatory have been attributed to them.1 The dermatophytes are a group of fungi, which parasitize the stratum c...

Dermatomycoses caused by Microsporum canis are frequent in domestic animals and easily transmissible to humans. Several proteases secreted by this fungus were identified as potential virulence factors, but the construction of deficient strains is required to investigate their role in the pathogenesis of the disease. Using target genes encoding two of these proteases, a first evaluation of the u...

Dermatophytes are a uniquely pathogenic group of fungi that cause most common fungal infections globally. The major cause of athlete's foot is Trichophyton rubrum, a pathogen of human skin. A recent paper in this journal reported the sequencing and analysis of five additional genome sequences, including that of Trichophyton rubrum. These five join the existing two additional genome sequences to...

Dermatophytosis is common in superficial fungal infection of keratinized tissues. Although common, the precise size of the problem defies measurement. To access the clinicoepidemiological profile of dermatophyte infection. To identify the species of fungus and to compare the clinical diagnosis by KOH smear and culture. Two hundred clinically suspected cases of dermatophytosis were subjected to ...

background: in the present study, a pcr-rflp based molecular technique was designed to rapid identification of der­matophytes in clinical specimens. skin scrapings obtained from human cases suspected to dermatophytosis were studied in or­der to identify involved etiological fungi. methods: in this experimental study, the specimens (skin scrapings) of patients referred to mycology department of ...

background: medicinal plants synthesize a vast array of secondary metabolites that are important for human life. for medicinal purpose, antimicrobial activity of substances derived from plant extracts has been recognized for many years. pimpinella anisum l. (apiaceae) and illicium verum hook. f. (illiciaceae) plant species, have been used for treatment of infectious diseases in iranian traditio...

introduction: trichophyton rubrum is one of the most common species of dermatophytes which affects superficial keratinous tissue. it is not especially virulent but it can be responsible for considerable morbidity. although there are different therapeutic modalities to treat fungal infections, clinicians are searching for alternative treatment because of the various side effects of the present t...

A proportion of dermatophyte infections fail to respond to normally adequate courses of griseofulvin and topical antifungal therapy. The organism Trichophyton rubrum was isolated from 96% of 50 patients studied, but no instances of in vitro resistance were seen. Of these patients, 57% had an underlying condition, commonly hay fever/asthma, atopic eczema, collagen disease or ichthyosis. Defectiv...

Introduction: The most common cutaneous fungal infections are caused by dermatophyte fungi such as Microsporum, Trichophyton, and Epidermophyton. In this study, the epidemiologic trends predominant organisms causing dermatophytosis in Urmia, Northwest Iran, were identified.Aims objectives: To get better perception of distribution authors studied identification isolated dermatophytes from human ...