The rarity of thrombotic complications and overt clinical disease are possibly the only features that distinguish atherosclerosis in animals from the same condition in man. Yet the reason (or reasons) why a comparatively bland vascular disorder now presents as a lethal myocardial disease of high prevalence in modern western man is still largely unknown. A historical approach to the problem has ...

É de senso comum que a gestão da mudança de requisitos exerce papel fundamental no processo de desenvolvimento de software, principalmente no que tange à qualidade. Para que se possa gerenciar a mudança de requisitos de forma efetiva e precisa, torna-se indispensável o uso de informações de rastreabilidade, que por sua vez, torna possível a realização da análise de impacto. Para que se possa ef...

Regras de negócio (RNs) são declarações cujo objetivo é influenciar, ou guiar, o comportamento de um negócio [8]. Elas têm por objetivo definir as características do negócio que norteiam a execução dos requisitos funcionais de um software. Pesquisadores argumentam que a sensibilidade das RNs às mudanças de requisitos faz com que elas devam ser tratadas de forma mais adequada e sistemática duran...

A computação ubíqua é caracterizada como um novo paradigma onde o poder de processamento está disponível de forma onipresente e imperceptível no ambiente do usuário. Explorar este paradigma em projetos de software permite tratar soluções para problemas até então inviáveis devido a suas características gerais de utilização e acesso. Assim, essa pesquisa visa evoluir uma abordagem de apoio à defi...

Background: Caregiver input has informed the design of a valid electronic patient-reported outcome (PRO) measure for use in pediatric rehabilitation. This proxy assessment may be further developed to expedite and enhance patient-centered care planning processes, but user input is first needed to finalize the core requirements that will guide its design. Objective: The objective of this study wa...

BACKGROUND Caregiver input has informed the design of a valid electronic patient-reported outcome (PRO) measure for use in pediatric rehabilitation. This proxy assessment may be further developed to expedite and enhance patient-centered care planning processes, but user input is first needed to finalize the core requirements that will guide its design. OBJECTIVE The objective of this study wa...

PURPOSE Previous research into the impact of pro-eating disorder (pro-ED) websites has predominantly been undertaken using experimental and survey designs. Studies have used both clinical and non-clinical (college student) samples. The present study aimed to explore the underlying functions and processes related to the access and continued use of pro-ED websites within a clinical eating disorde...

Intrinsic parallelism is shown to have application beyond schemata and o-schemata. More general objects called formae are introduced and general operators which manipulate these are introduced and discussed. These include random, respectful recombination. The extended formalism is applied to various common representations and standard operators are analysed in the light of the formalism.

background: leishmaniasis is a worldwide disease prevalent in tropical and sub- tropical countries in the world. characterization of inflammatory responses produced in cutaneous leishmaniasis has not yet been completed. methods: the specific primers were designed for ten pro-inflammatory genes including ccl4, ccl3, tnf-α, il-1α, il-12p35, il-12p40, ccl5, ccr5, il-1β and ifn- γ and their express...

Tinnitus Retraining Therapy (TRT) is a structured method of tinnitus treatment that has been performed since 1990. The TRT Initial Interview form was developed to guide clinicians in obtaining essential information from patients that would specify treatment needs. The TRT Follow-up Interview form is similar to the initial interview form and is designed to evaluate outcomes of treatment. The cli...