conclusions hexagonal water has no significant effect(s) on total cholesterol, hdl, and ldl; however, more experiments are needed to clarify all aspects of hexagonal water consumption on diabetes. background diabetes is one of the most prevalent abnormalities in all over the world. nowadays, there are lots of attempts to reduce its disturbances and defects by changing life style to access some ...

Edaravone, a synthetic-free radical scavenger, has been reported to reduce ischemia-reperfusion-induced renal injury by improving tubular cell function, and lowering serum creatinine and renal vascular resistance. The present study investigated the effect of edaravone in diabetes mellitus-induced nephropathy in rats. A single administration of streptozotocin (STZ, 55 mg/kg, i.p.) was employed t...

Purpose: To investigate the effect of JTXK granule on the expression pattern of miRNA in pancreatic tissue of KKAy diabetic mice, and to explore the molecular mechanism and pathways of JTXK granule in anti-diabetic effect. Methods: We used high fat diet (HFD) to induce the KKAy diabetic mice and screened the differentially expressed miRNAs (DEMs) between JTXK-treated group (n = 6) and the diabe...

objectives: turnip leaf has been used in folk medicine of iran for the treatment of diabetes. however,so far no scientific study has been done to support its use in traditional medicine. the present study was carried out to evaluate the possible hypoglycemic efficacy of aqueous extract of turnip leaf (aetl) in diabetic rats. materials and methods: alloxan-induced diabetic rats were orally treat...

background and objective: diabetes mellitus is common endocrine disease cause learning and memory impairment. this study was done to evaluate the effect of quercetin on learning and memory in stz-induced diabetic rats was investigated. methods: in this experimental study, 40 male wistar rats were randomly allocated into five groups: control, quercetin - treated control, diabetic and quercetin -...

objectives the aim of this study was to evaluate the biological effects of opium on the number of peripheral blood cells and red blood cells (rbcs) indices in diabetic rats. materials and methods peripheral blood samples were collected from diabetic, opium-addicted, diabetic opium-addicted and normal male and female rats and hematological parameters were measured. results the mean number of whi...

The progressively growing number of patients with end-stage renal failure (ESRF) associated with diabetes mellitus and requiring renal replacement therapy (RRT) stimulated both nephrologists and diabetologists to investigate the mechanisms linking hyperglycaemia to diabetic renal failure and to set up measures to prevent the onset and slow the progression of diabetic nephropathy. Over the last ...

OBJECTIVE Ghrelin is a newly discovered peptide, which was first demonstrated in the epithelium of rat stomach. The purpose of the study was to examine the effect of ghrelin on glucagon secretion from pancreatic tissue fragments of normal and diabetic rats. METHODS Diabetes was induced by streptozotocin (60 mg Kg body weight 1) given intraperitoneally. Four weeks after the onset of diabetes, ...

The potential role of morin in the treatment of diabetes along with its antihyperlipedemic effects was studied in streptozotocin-induced diabetic rats. Diabetes was induced in male Wister rats by single intraperitoneal injection (i.p) of 50 mg/kg streptozotocin. Morin was administered orally at doses of 50 and 100 mg/kg for 45 days. At the end of this experiment the effect of morin on plasma gl...

Oxidative stress may play a key role in the pathogenesis of diabetic nephropathy. Propolis and its extract have antioxidant properties. The effect of ethanolic extract of propolis against experimental diabetes mellitus-associated changes was examined. Diabetes was induced experimentally in rats by i.p. injection of streptozotocin (STZ) in a dose of 60 mg/kg bwt for 3 successive days. Blood urea...