We established depressive symptoms prevalence in 100 patients recommended to our obesity clinic and we started antidepressant treatment in 41 of them. It has been noted that administration of SSRI leads to weight reduction after 6 months, but is followed by a weight increase later. Our experience shows that 12 months long administration of bupropion and tianeptine leads to continuous weight los...

A worldwide epidemic exists with respect to diabetes mellitus because of increased rates of obesity. There is a significant correlation between obesity and insulin resistance and obesity causes the increase in the severity of the disease. The adipose tissues in the visceral region function as an endocrine organ that produces certain proteins with role in glucose homeostasis. The expression leve...

BACKGROUND Diabetes mellitus is a well-recognized risk factor for ischaemic stroke. Stroke in diabetic patients is different from stroke in non-diabetics from several perspectives. There is no local study on this topic. This is the first study from Pakistan, in which pattern of stroke in diabetics have been described and compared with non-diabetics. The object of this study was to compare patte...

Background Ectopic pregnancy after hysterectomy is a very uncommon event, but its frequency is increasing. Since first reported by Wendler in 1895, 71 cases of post-hysterectomy have been reported. Case A woman, 2 years after an abdominal supracervical hysterectomy, presented with a ruptured fallopian tube ectopic pregnancy. Conclusion Any woman, even after hysterectomy but with ovaries in ...

esistin, an adipocyte secreted hormone, has been suggested to link obesity with type 2 diabetes and insulin resistance in rodent models, but its relevance to human diabetes remains uncertain. The aim of this study was to investigate the relationship between serum resistin concentrations with markers of insulin resistance and obesity in type 2 diabetes and non-diabetic obese subjects. Materials ...

In addition to adipose tissue, recent studies suggest that skeletal muscle may also be a source of low-grade inflammation, particularly in inactive and/or overweight individuals. The aim of this study was to examine the presence of macrophages in skeletal muscle from obese subjects with type 2 diabetes (T2D) before and after a 9-month exercise program (vs. a non-exercising control group) (Study...

OBJECTIVE The present study investigated the impact of overall obesity defined by BMI and abdominal obesity defined by WC on vascular atherosclerotic changes in obese and normal weight diabetic subjects. DESIGN AND METHODS 285 subjects were divided according to presence diabetes mellitus (DM) and obesity: Group 1 included 144 nonobese subjects without DM; Group 2 consisted of 141 type 2 diabe...

The clinical effectiveness of metformin was compared with that of chlorpropamide in closely similar groups of 216 non-obese patients recently diagnosed as cases of maturity-onset diabetes that could not be controlled by diet. The incidences of primary and secondary drug failures in each group and the numbers of patients satisfactorily maintained on each of the hypoglycaemic agents throughout th...

the ophthalmologic outcomes of diabetes were important. this research is conducted to assess the relation between diabetes and intraocular pressure changes in the patients of avicenna hospital, compared with healthy persons referring to the facility. with cross-sectional research, 400 persons including 200 diabetics and non-diabetics were selected on a random basis over one year in 2012. resear...

Background: Objectives of current study were to find out the proportion types diabetes and know factors for adverse maternal fetal outcome in pre-gestational gestational at a tertiary care Institute compare outcomes between GDM.Methods: Prospective descriptive conducted department obstetrics gynaecology, center over period 1 year. The inclusion criteria were: (pregnant women with type & 2 m...