Microanigiographlic examinatioin of the pulmoniary arterial svstem in 12 n1ewborn in1fants with conicomitanit steniosis or atresia of the aortic anid mitral orifices showed that the intrapulmonary arterial pattern is inifluenced by the state of the forameni ovale. In inifanlts with aortic atresia with a prematuirely closed foramein ovale, that is cases in which the left side of the heart is a c...

Doppler echocardiography is a method for detecting the direction and velocity of moving blood within the heart. As will be seen in this program, the technique may be used for detection of cardiac valvular insufficiency and stenosis as well as a large number of other abnormal flows. The current interest in Doppler echocardiography has reached a remarkable level in just the past few years. Dopple...

A Case of calcific constrictive pericarditis in ayoung White woman with a convincing history of previous aCute rheumatic fever complicated by a possible Valvular lesion is presented. Cardiac catheterization confirmed the suspicion of significant cardiac compression. Successful pericardiectomy was carried out, but microscopical examination of the excised pericardium failed to demonstrate a cause...

A 49-year-old female took low-dose pergolide (625 microg daily) for approx. 5 years (approximately cumulative dose 1.140 g/5 years) for the treatment of restless legs syndrome. She developed moderate to severe mitral and aortic valve insufficiency, requiring semi-urgent double-valve replacement. The initial diagnosis of rheumatic valve disease was refuted on histological examination of the valv...

BACKGROUND Analogous to stenotic valve area in the assessment of valvular stenosis, regurgitant orifice area (ROA) represents a fundamental parameter to assess valvular insufficiency. However, this parameter has not been routinely available up to now. In this study, we introduce the concept and provide the methodology to calculate regurgitant orifice area noninvasively, based on the analysis of...

Since 2007, the Netherlands has experienced a large Q fever outbreak. To identify and quantify risk factors for development of chronic Q fever after Coxiella burnetii infection, we performed a case-control study. Comorbidity, cardiovascular risk factors, medications, and demographic characteristics from 105 patients with proven (n = 44), probable (n = 28), or possible (n = 33) chronic Q fever w...

Congenital anomalies of the aortic valve are common and are associated with progressive valvular insufficiency and/or stenosis. In addition, aneurysm, coarctation, and dissection of the ascending aorta and aortic arch are often associated conditions that complicate patient management and increase morbidity and mortality. These associated aortopathies are commonly attributed to turbulent hemodyn...

Microanigiographlic examinatioin of the pulmoniary arterial svstem in 12 n1ewborn in1fants with conicomitanit steniosis or atresia of the aortic anid mitral orifices showed that the intrapulmonary arterial pattern is inifluenced by the state of the forameni ovale. In inifanlts with aortic atresia with a prematuirely closed foramein ovale, that is cases in which the left side of the heart is a c...

Patients with ankylosing spondylitis (AS) may develop cardiovascular manifestations ranging from asymptomatic forms to life threatening conditions. The most important cardiovascular manifestation of AS is aortitis, which frequently involves the aortic root and the ascending aorta leading to valvular insufficiency. The extension of the subaortic fibrotic process into the interventricular septum ...

Systolic ejection clicks, often associated with cardiac disease, can be distinguished from mid-systolic clicks of mitral and tricuspid origin, which are frequently benign. A different mid-systolic sound has been recognized, with timing similar to the mid-systolic clicks, which is associated with aortic insufficiency. This report describes a case in which such a sound was identified prior to aor...