Hypertension is a pathology caused by increased systolic and/or diastolic blood pressure. The disease can be controlled various antihypertensive drugs. This study simulates the response of human cardiovascular and renal systems to action angiotensin II receptor blocker azilsartan medoxomil, taking into account dual combinations this drug with thiazide diuretic hydrochlorothiazide, $upbeta$-bloc...

We have investigated the prevalence of hypertension and the response of blood pressure to operation in 87 patients with lone aortic valve disease who underwent aortic valve replacement. In patients with aortic stenosis alone 26% were hypertensive pre-operatively (age and sex adjusted blood pressure greater than 160 systolic and or greater than 95 mmHg diastolic) and 24% were hypertensive post-o...

BACKGROUND The aim of the present study was to examine whether exercise blood pressure can be used to predict the development of hypertension in normotensive middle-aged adults. METHODS AND RESULTS We investigated 7082 normotensive subjects who were annually screened in a tertiary medical center and completed maximal treadmill exercise tests at each visit. After the initial 3 years, subjects ...

OBJECTIVE The level of agreement between two blood pressure (BP) reading methods, auscultatory vs oscillometric, was examined using a mercury sphygmomanometer and an electronic device in children and adolescents with different levels of obesity. The readings were compared to determine their impact on the diagnosis of pre-hypertension/hypertension. METHODS Blood pressure readings were taken in...

BACKGROUND Individuals with prehypertension are at a high risk of developing hypertension. Little is known about the predictors of progression from prehypertesion to hypertension in rural Chinese adults. METHODS A population-based sample of 15 061 rural Chinese aged > or =35 years with prehypertension free cardiovascular diseases at baseline were followed-up from 2004-2006 to 2008. Incident h...

CONTEXT Lead exposures have been shown to be associated with increased blood pressure and risk of hypertension in older men. In perimenopausal women, skeletal lead stores are an important source of endogenous lead exposure due to increased bone demineralization. OBJECTIVE To examine the relationship of blood lead level with blood pressure and hypertension prevalence in a population-based samp...

BACKGROUND Parental hypertension is used to classify hypertension risk in young adults, but the long-term association of parental hypertension with blood pressure (BP) change and risk of hypertension over the adult life span has not been well studied. METHODS We examined the association of parental hypertension with BP change and hypertension risk from young adulthood through the ninth decade...

hypertension is one of the most important modifiable risk factors of vascular heart disease. control of hypertension in different age groups has a significant effect upon the control and prevention of vascular heart disease. a familial pattern is observed in the distribution of blood pressure in different societies. family history of hypertension has a profound effect on the future risk of deve...

The results of several large studies of hypertension and follow up studies on insured people have indicated that the lower the blood pressure the better for longevity. These studies excluded subjects with overt ischaemia. More recently long term studies of hypertension that included patients with more severe forms of hypertension and did not exclude those with overt ischaemia have shown a J sha...

Data regarding the tolerance of ACE inhibitors in old age are sparse, despite this class of compound being regarded as one of the first-line agents for the treatment of hypertension. In the present trial, the efficacy and tolerance of the ACE inhibitor fosinopril was examined over a period of 12 weeks in an open trial of hypertensive patients aged over 60 years with diastolic hypertension (dias...