One of the earliest manifestations of potassium depletion is a reduction in the ability of the kidneys to elaborate a concentrated urine.' This defect has been shown to result at least in part from a decrease in the concentration of sodium in the interstitial fluids of the renal medulla and papilla.9 The disturbance in renal concentrating ability may exist without impairment of glomerular filtr...

This study investigates the effect on stock prices of seasoned equity offerings. The results demonstrate that the announcement of equity otlerings reduces stock prices significantly. For industrial issues, regression results indicate that announcement day price reduction is significantly and negatively related to the size of the equity offering. The results appear not to be explained by changes...

By ALLAN J. EIISLEV D ILUTION ANEMIA 011 HYDIIE\IIA is a condition characterized by an increase in total plasma volume without corresponding change in total red cell volume. Certain anemias complicating pregnancy,’ malnutrition,2 netirasthenia,3 and the t.herapetttic use of phenylbutazone4 and steroids5 have been considered to he caused by such a dilution of the red cell mass. The erythropoieti...

Bovine semen experimentally contaminated with Leptospira santarosai serovar Guaricura was submitted to the modified EMJH medium with 5-fluorouracil (300mg/L) and nalidixic acid (20mg/L), named as "selective medium" and using the serial dilution technique, in order to evaluate the percentage of recovery of the added microorganism. The selective EMJH medium was found with higher percentage of rec...

BACKGROUND To date different vaginal gel microbicides have been evaluated in phase 2b/3 trials, but none have demonstrated effectiveness for preventing HIV infection. Failure to demonstrate effectiveness however does not necessarily indicate that a product is truly inefficacious, as several sources of efficacy dilution may compromise our ability to identify products that may have been truly eff...