An antiserum that recognizes the three types of pyrimidine dimers induced by UV-light in DNA was used to monitor their removal from eukaryotic cell nuclei. Cells able to excise dimers display a similar removal pattern: a fast process completed within a few hours leaving many dimers in the DNA.

LAMP-based platform for SARS-CoV-2 RNA detection incorporating beads to remove primer-dimers, enhance fluorescent signal and stop the reaction after amplification.

We investigate the broadening of the 2s energy level of a Li atom outside a Si(001) surface using a first principles approach. The covalent nature of the Si surface produces large variations in Li energy level widths as a function of lateral position across the surface. The widths above symmetric Si dimers are predicted to be much larger than above buckled Si dimers, suggesting that charge tran...

Using potassium hexacyanoferrate (III)-sodium acetate as oxidant, the oxidative coupling reaction of isorhapontigenin and resveratrol in aqueous acetone resulted in the isolation of three new indane dimers 4, 6, and 7, together with six known stilbene dimers. Indane dimer 5 was obtained for the first time by direct transformation from isorhapontigenin. The structures and relative configurations...

Insulin receptors from turkey erythrocyte membranes exist as monomers and dimers when membranes are solubilized with detergent. We examined the ability of monomers and dimers to act as protein kinases to effect both autophosphorylation of the receptor and phosphorylation of an exogenous substrate. After separation by sucrose-density-gradient centrifugation, only receptor dimers show significant...

The normally monomeric 01 subunit of Escherichia coti tryptophan synthetase forms dimers and higher order aggregates following exposure to high urea concentrations and removal of the urea by dialysis. The maximum yield of cx chain dimers is approximately 2%. Dimers of certain combinations of different enzymatically inactive mutant (Y monomers exhibit the missing enzymatic activity. In such hete...

The normally monomeric 01 subunit of Escherichia coti tryptophan synthetase forms dimers and higher order aggregates following exposure to high urea concentrations and removal of the urea by dialysis. The maximum yield of cx chain dimers is approximately 2%. Dimers of certain combinations of different enzymatically inactive mutant (Y monomers exhibit the missing enzymatic activity. In such hete...

Infrared multiphoton dissociation spectra of three homogeneous and two heterogeneous proton-bound dimers were recorded in the gas phase. Comparison of the experimental infrared spectra recorded in the fingerprint region of the proton-bound dimers with spectra predicted by electronic structure calculations shows that all modes which are observed contain motion of the proton oscillating between t...

Background. Strategies combining pretest clinical assessment and D-dimers measurement efficiently and safely rule out venous thromboembolism events (VTE) in low- and intermediate-risk patients. Objectives. As process of ageing is associated with altered concentrations of coagulation markers including an increase in D-dimers levels, we investigated whether D-dimers could reliably rule out VTE ac...

BACKGROUND AND PURPOSE Cerebral sinus thrombosis (CST) needs to be considered in the differential diagnosis of all patients with acute headache. Early diagnosis is essential because early treatment may prevent morbidity and may even be life-saving. Definite exclusion, however, needs advanced neuroradiologic diagnostics, which are not readily available in many hospitals. Because measurement of D...