Meningococcal meningitis and septicaemia remain a serious global health threat. This review focuses on the epidemiology of meningococcal disease following the recent implementation of effective vaccines and the potential utility of a vaccine against serogroup B meningococcus.

There are many options for controlling the spread of animal diseases. Some diseases have been treated as public sector problems and many nations have tried to control disease spread by purchasing sick animals from farmers. Government agencies have purchased breeding stock that might transmit diseases. Government agencies have purchased animals that might otherwise have gone to the slaughterhous...

BACKGROUND Peptic ulcer disease is the cause for dyspepsia in about 10% of patients. 95% of duodenal and 70% of gastric ulcers are associated with Helicobacter pylori. Eradication of H pylori reduces the relapse rate of ulcers but the magnitude of this effect is uncertain. OBJECTIVES The primary outcomes were the proportion of peptic ulcers healed initially and proportion of patients free fro...

Correspondence to: Sun-Young Lee Department of Internal Medicine, Konkuk University School of Medicine, 120 Neungdong-ro, Gwangjin-gu, Seoul 143-729, Korea Tel: +82-2-2030-7505, Fax: +82-2-2030-7748, E-mail: [email protected] pISSN 1976-2283 eISSN 2005-1212 http://dx.doi.org/10.5009/gnl14499 Helicobacter pylori is a major cause of peptic ulcer disease (PUD) recurrence, and thus eradication is ...

BACKGROUND/AIMS Eradication of Helicobacter pylori is widely accepted as initial therapy for low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma. However, approximately 20% of patients with this disease are not responsive to H. pylori eradication therapy. The aim of this study was to assess remission and relapse rates of low-grade gastric MALT lymphoma after H. pylori eradicatio...

We analyze the implications of geographical heterogeneities and externalities on health macroeconomic outcomes by extending a basic epidemiological-macroeconomic model to spatial dimension. Because people's migration commuting across different regions, disease may spread also in areas far from those which outbreak originally occurs thus status (i.e., prevalence) specific regions depend other as...

Abstract Background The development of direct-acting antivirals (DAA) for HCV has revolutionized the treatment HCV, including its in patients with HIV coinfection. aim this study was to compare changes liver function between coinfected and monoinfected cirrhosis who achieved eradication by DAA. Methods Patients pre-treatment diagnosis cirrhosis, consecutively enrolled multicenter PITER cohort, ...

BACKGROUND Yaws, one of the 17 neglected tropical diseases (NTDs), is targeted for eradication by 2020 in resolution WHA66.12 of the World Health Assembly (2013) and the WHO roadmap on NTDs (2012). The disease frequently affects children who live in poor socioeconomic conditions. Between 1952 and 1964, WHO and the United Nations Children's Fund (UNICEF) led a global eradication campaign using i...

OBJECTIVE Conflicting reports have noted a possible association linking eradication of Helicobacter pylori with aggravation of gastroesophageal reflux (GER) disease. We prospectively evaluated the effect of eradication of H pylori on GER symptoms and epigastric pain and the association among these 3 parameters in a pediatric cohort. METHODS Patients who were referred for gastroscopy were eval...

BACKGROUND The aim of this study was to investigate the effect of Helicobacter pylori (H. pylori) eradication in selected H. pylori-positive patients with a primary diagnosis of gastro-esophageal reflux disease (GERD) by using the 3-h postprandial esophageal pH monitoring. METHODS We recruited patients with erosive esophagitis at endoscopy and H. pylori infection at histology, successfully cu...