in order to improve particle properties, new processes combining granulation and crystallization are being developed. this work deals with the spherical crystallization process by the quasi-emulsion mechanism applied to carbamazepine, a pharmaceutical drug. the aim of the present study was to produce of spherical grains made of mall crystals of a drug that have adequate properties for direct co...

An optical interferometry system has been used to study the dynamics of the dissolution of anorthite (010) cleavage surfaces. With this technique, it is possible to measure directly the surface retreat of alumino-silicates as a function of time and thereby the dissolution rate using a new application of interferometry. Vertical scanning white light interferometry (VSWLI) provides about 0.5 to 1...

the sargaz granitic intrusion has been emplaced in sargaz ophiolitic suite, south-east of sanandaj-sirjan metamorphic zone, south of kerman province. the central part of the intrusive body contains pinkish coarse-grained granite, but the fractured northern part, neighboring chah-mazraeh fault, has been subjected to pervasive na-metasomatism and related subsolidus reactions. in the northern alte...

Theoretical calculations have shown that acidic candies may be potentially erosive upon consumption. However, little is known about the protective effect of adding calcium to potentially erosive candies and about the protective effects of saliva that cannot be fully accounted for by theoretical calculations. Therefore, the aims of this study were to (1) determine the erosive potential of acidic...

The Sargaz granitic intrusion has been emplaced in Sargaz ophiolitic suite, south-east of Sanandaj-Sirjan metamorphic zone, south of Kerman province. The central part of the intrusive body contains pinkish coarse-grained granite, but the fractured northern part, neighboring Chah-Mazraeh fault, has been subjected to pervasive Na-metasomatism and related subsolidus reactions. In the northern alte...

megaloporous controlled release tablets of diclofenac sodium (ds) were prepared with two kinds of granules. one of them is the restraining-phase matrix granule (rmg) and it controls the release rate of the drug. the other one is the soluble housing-phase matrix granule (hmg) and controls liquid penetration into the system. carnauba wax and eudragit l 100 polymers were used to constitute the res...

Magnetic resonance imaging is used to study changing microstructure and molecular motion during dissolution of poly(vinyl alcohol) (PVA) in water. One-dimensional water concentration profiles were measured as a function of distance from the polymer-solvent interface. Diffusion-weighted profiles were used to calculate the spatial variation of the self-diffusion coefficient of water. The results ...

In situ scanning tunneling microscopy (STM) of the dissolution of a Cu(100) electrode in aqueous chloride media (HC1) was employed to find the mechanism of reaction at the atomic level. Imaging the surface at potentials where no dissolution occurred resulted in a clear ( 4 2 x 42)R45' C1 structure with an observed C1-C1 distance of 0.35 f 0.02 nm, in agreement with previous ultrahigh vaccum sur...

Assessing the ability of soil microorganisms to dissolute poorly soluble native calcite to supply Ca2+ is a new area to be explored in reclaiming sodic soils by supplying adequate Ca2+ and reducing the recurrent sodicity. Hence, the present study aimed to isolate a calcite dissolving bacteria (CDB) from calcareous sodic soils and to understand the mechanism of calcite dissolution. Of the 33 CDB...

The aim of the current investigation was to develop a Sustained release tablet of Donepezil Hydrochloride using nongelling polymer in order to overcome the problem of dose dumping. Viscarin GP-209 was used as a non-gelling release modifying agent. The formulated granule blends were evaluated for powder properties. Prepared tablets were subjected to post compression evaluations. In-vitro dissolu...