نتایج جستجو برای: dmc1

تعداد نتایج: 335  

Journal: :Genetics 2011
Xin Chenglin Li Ewelina Bolcun-Filas John C Schimenti

Chiasmata resulting from interhomolog recombination are critical for proper chromosome segregation at meiotic metaphase I, thus preventing aneuploidy and consequent deleterious effects. Recombination in meiosis is driven by programmed induction of double strand breaks (DSBs), and the repair of these breaks occurs primarily by recombination between homologous chromosomes, not sister chromatids. ...

2013
Fabrizia Carofiglio Akiko Inagaki Sandra de Vries Evelyne Wassenaar Sam Schoenmakers Christie Vermeulen Wiggert A. van Cappellen Esther Sleddens-Linkels J. Anton Grootegoed Hein P. J. te Riele Bernard de Massy Willy M. Baarends

In mammalian meiotic prophase, the initial steps in repair of SPO11-induced DNA double-strand breaks (DSBs) are required to obtain stable homologous chromosome pairing and synapsis. The X and Y chromosomes pair and synapse only in the short pseudo-autosomal regions. The rest of the chromatin of the sex chromosomes remain unsynapsed, contains persistent meiotic DSBs, and the whole so-called XY b...

Journal: :Agronomy 2023

Recombinases are in part responsible for homologous recombination and genome integrity during DNA repair. DMC1 has a typical RecA domain, belongs to the recombinase superfamily. The reactive oxygen species (ROS) as potent damage agent is produced seed germination under stress conditions. repair should be initiated immediately allow subsequent seedling development. In this study, we attempted ch...

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