The treatment options for hepatocellular carcinoma (HCC) are liver resection, liver transplantation, or local ablation (e.g., percutaneous ethanol injection, cryosurgery, radio-frequency ablation, and chemoembolization). Most patients are not eligible for curative resection because of the location of the tumor or the severity of liver disease. For many of these patients, liver transplantation r...

selective deficiency of immunoglobulin a (iga) is the most frequent primary hypogammaglobulinemia. as some iga-deficient patients have iga antibodies in their plasma which may cause anaphylactic reactions, blood centers usually maintain a list of iga-deficient blood donors to prepare compatible blood components. in this study we determined the incidence of selective iga deficiency (sigad) in no...

in the september and november 2006 issues of nature clinical practice nephrology , two articles regarding living unrelated kidney donor transplantation alluded to the practices in iran. having served in the planning, supervision and implementation of various aspects of health care in iran, including organ transplantation (anh), and as transplant nephrologists who have actively participated in t...

A s OF MARCH 31. 1994. there were 34.493 patients on the United Network for Organ Sharing (UNOS) waiting list. I up from 13.115 in December 31. 1987. an increase of 263%. Of these. 3264 awaited liver transplantation (OLT). up from 449 in 1987 (7'27% increase). The supply of organ donors. on the other hand. underwent a marginal increase between 1988 and 1990 (from 4085 to 4514), and has remained...

Fourth-generation assays for the simultaneous detection of human immunodeficiency virus (HIV) antigen and antibodies are available on the international market and are currently used for blood donor screening and for HIV diagnosis. In this study we evaluated the performance of the novel automated fourth-generation ADVIA Centaur® HIV Ag/Ab Combo assay. The assay detected seroconversion at the sam...

Chagas disease (CD) is a parasitic infection that originated in the Americas and is caused by Trypanosoma cruzi. In the last few years, the disease has spread to countries in North America, Asia and Europe due to the migration of Latin Americans. In the Brazilian Amazon, CD has an endemic transmission, especially in the Rio Negro region, where an occupational hazard was described for piaçaveiro...

Human T-lymphotropic virus (HTLV) infection has been under enhanced surveillance in England and Wales since 2002, however, little is known about testing patterns. Using data from two surveillance systems held at Public Health England, we described HTLV antibody testing patterns between 2008 and 2013 and the demographic and clinical characteristics of persons diagnosed with HTLV in England and W...

Malaria in Brazil is endemic in the Amazon region, but autochthonous cases with low parasitaemia occur in the Atlantic Forest area of the country. According to Brazilian legislation no test is mandatory for blood donors from non-endemic areas. However if they have traveled to malaria transmission regions they are deferred for six months before they can donate. This report describes a transfusio...

The safety of any blood transfusion begins with the proper selection of donors. The physician must take care that removal of blood does not harm the donor and that the potential risk to the recipient due to disease conditions in donor must be kept to minimum. All blood donors should be in enough good health to be able to tolerate a short period of hypotension and bradycardia that occurs due to ...