Spermatozoa generate reactive oxygen species (ROS) in physiological amounts which play a role in sperm functions during sperm capacitation acrosome reaction (AR) and oocyte fusion. In addition damaged sperm are likely to be the source of ROS. The most important ROS produced by human sperm are hydrogen peroxide superoxide anion and hydroxyl radicals. Besides human seminal plasma and sperm posses...

D ioxygen is a highly important, yet toxic, molecule that reacts in vivo to produce reactive oxygen species such as superoxide, peroxides, hydroxyl radicals, and other related species. Those species play important roles in healthy organisms, and they are implicated in aging and a wide range of disease processes as well. The contents of this Special Feature on Reactive Oxygen Species in Chemistr...

Background: Avian spermatozoa are characterized by high proportions of poly unsaturated fatty acid, associated with increased susceptibility to Reactive Oxygen Species and lipid peroxidation. Recent advances in poultry reproduction have focused on the potential of Reactive Oxygen Species as one of the prime mediators of infertility. Oxidative stress is the result of imbalance between the Reacti...

A RANDOMIZED CLINICAL TRIAL by the Acute Respiratory Distress Syndrome Network (1) demonstrated a 22% reduction in mortality in patients by reducing the tidal volume for mechanical ventilation from the conventional setting of 12 ml/kg to a lower setting of 6 ml/kg. This dramatic decrease in mortality has stimulated significant interest in the mechanisms of ventilatorinduced lung injury and the ...

Abstract The breaking of dormancy mediated by reactive nitrogen species (RNS) is related to the accumulation oxygen (ROS) in germinating embryos but underlying mechanism unclear. objectives this study were: (1) explore relationship between RNS-mediated release and ROS Sorbus pohuashanensis ; and, (2) investigate relationships among germination time, metabolism, endogenous hormone synthesis. We ...

This study investigated the correlation between sperm motion parameters obtained by a computer-assisted semen analyzer and levels of reactive oxygen species in unwashed semen. In total, 847 patients, except for azoospermic patients were investigated. At the time of each patient's first consultation, semen parameters were measured using SMAS™ or CellSoft 3000™, and production of reactive oxygen ...

SUN, XIAOCUN AND MICHAEL B. ZEMEL. 1 ,25Dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production. Obesity. 2007;15:1944–1953. Objective: We have previously shown 1 ,25-dihydroxyvitamin D3 [1 ,25-(OH)2D3] to inhibit mitochondrial uncoupling protein 2 (UCP2) expression in adipocytes and that in vivo suppression of calcitriol levels with calcium-rich diets increases UCP2 expr...